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. 2021 May:13:100217.
doi: 10.1016/j.bbih.2021.100217. Epub 2021 Feb 10.

Bell's Palsy after second dose of Pfizer COVID-19 vaccination in a patient with history of recurrent Bell's palsy

Affiliations

Bell's Palsy after second dose of Pfizer COVID-19 vaccination in a patient with history of recurrent Bell's palsy

Michael Repajic et al. Brain Behav Immun Health. 2021 May.

Abstract

Objective: To report a patient with history of recurrent Bell's Palsy who developed Bell's Palsy 36 ​h after the administration of the second dose of the Pfizer-BioNTech COVID-19 vaccine.

Case: The patient is a 57-year-old female with past medical history of 3 episodes of Bell's Palsy. She responded to prednisone treatment and returned to her baseline after each occurrence. Less than 36 ​h following the second dose of the vaccine, the patient developed a left Bell's Palsy. The facial droop progressed in severity over the next 72 ​h.

Conclusion: Given the expedited production of the vaccine and the novelty associated with its production, there may be information pertaining to side effects and individual response that remain to be discovered. Since both the Moderna and Pfizer Vaccine trials reported Bell's Palsy as medically attended adverse events, the association between vaccine administration and onset of symptomatic Bell's Palsy may warrant further investigation.

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Figures

Fig. 1
Fig. 1
Patient with a left facial droop.
Fig. 2
Fig. 2
Patient unable to close her left eye.

References

    1. Dong S., Jung A., Jung J. Recurrent Bell’s palsy. Clin. Otolaryngol. 2019 May;44(3):305–312. doi: 10.1111/coa.13293. - DOI - PubMed
    1. Graham B.S. Rapid COVID-19 vaccine development. Science. 2020 May 29;368(6494):945–946. doi: 10.1126/science.abb8923. Epub 2020 May 8. PMID: 32385100. - DOI - PubMed
    1. Moderna COVID-19 vaccine vaccines and related biological products advisory committee meeting (VRBPAC) Briefing Document December 17, 2020.
    1. Mutsch M., Zhou W., Rhodes P., Bopp M., Chen R.T., Linder T., Spyr C., Steffen R. Use of the inactivated intranasal influenza vaccine and the risk of Bell’s palsy in Switzerland. N. Engl. J. Med. 2004 Feb 26;350(9):896–903. doi: 10.1056/NEJMoa030595. PMID: 14985487. - DOI - PubMed
    1. Pfizer-BioNTech COVID-19 vaccine vaccines and related biological products advisory committee meeting (VRBPAC) Briefing Document December 10, 2020.