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. 1988 Apr;34(4):685-90.

Total, tartrate-resistant, and tartrate-inhibited acid phosphatases in serum: biological variations and reference limits

Affiliations
  • PMID: 3359601

Total, tartrate-resistant, and tartrate-inhibited acid phosphatases in serum: biological variations and reference limits

F Schiele et al. Clin Chem. 1988 Apr.

Abstract

We studied several factors affecting biological variation in serum acid phosphatases in a population of 1195 apparently healthy subjects four years old or older. We assayed total acid phosphatase activities in the presence of a transphosphorylating agent and using alpha-naphthyl phosphate as substrate. The main factors modifying total and tartrate-resistant acid phosphatases activities in serum are similar to those observed for total and bone alkaline phosphatases activities: age, sex, and hormonal state (puberty or menopause). The tartrate-inhibited acid phosphatase activity is, however, independent of biological variations. Finally, we propose reference limits for total, tartrate-resistant, and tartrate-inhibited acid phosphatases in serum.

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