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Case Reports
. 2020 Dec 29;11(1):8-12.
doi: 10.3390/clinpract11010003.

Not All That Shines on a PET Scan Is Cancer: A Silicone-Induced Granuloma Masquerading as Malignancy

Krishna Vedala  1 , Philip T Sobash  1 , Deborah Johnson  2 , Krishna Kakkera  3
Affiliations
Case Reports

Not All That Shines on a PET Scan Is Cancer: A Silicone-Induced Granuloma Masquerading as Malignancy

Krishna Vedala et al. Clin Pract. .

Abstract

PET/CT scans are frequently used in the initial workup of suspicious lesions but not all that lights up on a PET is cancerous. We wish to discuss a case of silicone-induced granuloma mimicking malignancy and the role of other imaging modalities for further workup.

Keywords: false positives; malignancy; pet imaging; radiology; siloconomas.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
(A) Mammogram demonstrating extracapsular rupture of the right breast, (B) mediastinal window chest CT demonstrating Linguine Sign of the left breast implant, (C) chest CT showing an 18 mm × 14 mm nodule in the right middle lobe causing concern for malignancy, and (D) the same image showing a 17 mm × 14 mm spiculated left lung nodule with concern for breast involvement.
Figure 2
Figure 2
PET/CT demonstrating increased uptake with multiple mediastinal lymph nodes with a nodule in the right middle lobe and a spiculated left lung nodule with concern for breast involvement: the black arrows point to areas of suspicion.
Figure 3
Figure 3
Non-caseating granuloma from a CT-guided biopsy of the left lung nodule showing an asteroid body (black arrow), a typical finding in granulomas.
See this image and copyright information in PMC

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