Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug 30;51(4):1682-1688.
doi: 10.3906/sag-2009-235.

Nutritional Status in patients with Neuro-Behçet's disease

Seyda Erdoğan  1 , Mine Hayriye Sorgun  1 , Müge Kuzu Mumcu  1 , Mustafa Aykut Kural  2 , Sefer Rzayev  1 , Canan Yücesan  1
Affiliations

Nutritional Status in patients with Neuro-Behçet's disease

Seyda Erdoğan et al. Turk J Med Sci. .

Abstract

Background/aim: The aim of this study was to assess the nutritional status and risk factors for malnutrition in Behçet’s disease (BD) and neuro-Behçet’s disease (NBD) patients.

Materials and methods: Medical recordings of 74 patients with BD without neurological involvement (BDWoNI), 72 patients with NBD, and 50 patients with other diseases (carpal tunnel syndrome or lumbar discopathy) were analyzed retrospectively. The serum analyses were performed in the inactive period of disease. Chronic malnutrition was defined as low levels of serum albumin (<3.5 g/dL) with normal sedimentation rate and normal serum CRP levels.

Results: Six (8.3%) of the patients in NBD group, 1 (1.4%) of the patients in BDWoNI group, and none of the patients in control group had chronic malnutrition (p = 0.029). Malnutrition rate was higher in NBD than control group (p = 0.036). The mean expanded disability status scale score was 2.92 ± 3.35 (range: 0–8) in patients with malnutrition and 1.44 ± 1.76 (range: 0–9) in patients without malnutrition in NBD group (p = 0.457). The ratio of patients having a progressive disease course was 33.3% and 7.6% in patients with and without malnutrition in NBD group, respectively. The median value of the duration of neurological involvement was 2 years (0–16) in patients with malnutrition and 6.5 years (0–18) in patients without malnutrition in NBD group (p = 0.046). There was no association between malnutrition and medications, disability scores, functional system involvement or findings on brain MRI.

Conclusion: Malnutrition was higher in patients with NBD. Higher disability level and progressive disease course may be risk factors for malnutrition in NBD. Malnutrition may be seen more frequently in earlier phases of neurological involvement.

Keywords: Behçet's disease; malnutrition; neuro-Behçet's disease.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST:

The authors declare that they have no financial or other conflicts of interest in relation to this research and its publication

References

    1. Akman-Demir G Serdaroglu P Tasci B. Clinical patterns of neurological involvement in Behçet’s disease: evaluation of 200 patients. 1999;122:2171–2182. - PubMed
    1. Kidd D Steuer A Denman AM Rudge P Neurological complications in Behçet’s syndrome. 1999;122:2183–2194. - PubMed
    1. Bharadwaj S Ginoya S Tandon P Gohel TD Guirguis J Malnutrition: laboratory markers vs nutritional assessment. Gastroenterology Report (Oxf); 4:272–280. - PMC - PubMed
    1. Santos Dos Queiroz Assunçao AT Foschetti AA Macêdo Uchôa DA Alves FN Assesment of nutritional and biochemical status in patients with rheumatoid arthritis undergoing pharmacological treatment. A pilot study. International Journal of Clinical and Experimental Medicine. 2016;9:4282–4290.
    1. Fukuda W Omoto A Oku S Tanaka T Tsubouchi Y Contribution of rheumatoid arthritis disease activity and disability to rheumatoid cachexia. Modern Rheumatology. 2010;20:439–443. - PubMed