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Case Reports
. 2021 Apr;25(2):102-104.
doi: 10.1016/j.jaapos.2020.11.007. Epub 2021 Feb 16.

Ophthalmic manifestations associated with SARS-CoV-2 in newborn infants: a preliminary report

Luis Gilberto Pérez-Chimal  1 , Gabriela García Cuevas  2 , Andreas Di-Luciano  3 , Pablo Chamartín  3 , Gabriela Amadeo  3 , María A Martínez-Castellanos  3
Affiliations
Case Reports

Ophthalmic manifestations associated with SARS-CoV-2 in newborn infants: a preliminary report

Luis Gilberto Pérez-Chimal et al. J AAPOS. 2021 Apr.

Abstract

COVID-19, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), affects people of all ages. The virus can cause multiple systemic infections, principally in the respiratory tract, as well as microvascular damage. Ocular manifestations of COVID-19 are uncommon in adults and children. We describe ophthalmic manifestations in newborns detected by slit-lamp examination, fundus examination, and fluorescein angiography. All patients showed edema and hemorrhagic conjunctivitis; fundus examinations revealed cotton wool spots and vitreous hemorrhage, and microvascular damage manifested as patchy choroidal filling, peripapillary hyperfluorescence, delayed retinal filling and venous laminar flow, and boxcarring on fluorescein angiography.

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Figures

Fig 1
Fig 1
External ophthalmic manifestations of SARS-CoV2 in newborns. A, Hemorrhagic conjunctivitis. B, Chemosis. C, Corneal edema and mild hemorrhagic conjunctivitis. D, Rubosis iridis and posterior synechiae.
Fig 2
Fig 2
Fundus manifestations of SARS-CoV2 in Newborns. A, Cotton wool spots. B, Retinal venous laminar flow and boxcarring sign on fluorescein angiography.
See this image and copyright information in PMC

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