Non-human primates and Leishmania immunity

doi:10.1016/j.cytox.2020.100038

. 2020 Oct 12;2(4):100038.

doi: 10.1016/j.cytox.2020.100038. eCollection 2020 Dec.

Non-human primates and Leishmania immunity

Sonia André¹, Vasco Rodrigues¹, Morgane Picard¹, Ricardo Silvestre^{2

3}, Jérôme Estaquier^{1

4}

Affiliations

¹ INSERM-U1124, Paris University, Paris, France.
² ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.
³ Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
⁴ Centre de Recherche du CHU de Québec, Laval University, QC, Quebec, Canada.

PMID: 33604562
PMCID: PMC7885871
DOI: 10.1016/j.cytox.2020.100038

Non-human primates and Leishmania immunity

Sonia André et al. Cytokine X. 2020.

. 2020 Oct 12;2(4):100038.

doi: 10.1016/j.cytox.2020.100038. eCollection 2020 Dec.

Authors

Sonia André¹, Vasco Rodrigues¹, Morgane Picard¹, Ricardo Silvestre^{2

3}, Jérôme Estaquier^{1

4}

Affiliations

¹ INSERM-U1124, Paris University, Paris, France.
² ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.
³ Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
⁴ Centre de Recherche du CHU de Québec, Laval University, QC, Quebec, Canada.

PMID: 33604562
PMCID: PMC7885871
DOI: 10.1016/j.cytox.2020.100038

Abstract

In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus Leishmania and classified as one of the neglected tropical diseases.

Keywords: CXCR5; Cytokines; Immunity; Leishmania; Monkeys; T cells; Tfh.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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References

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[1] da Silva A.V.A., Figueiredo F.B. Morphophysiological changes in the splenic extracellular matrix of Leishmania infantum-naturally infected dogs is associated with alterations in lymphoid niches and the CD4+ T cell frequency in spleens. PLoS Negl Trop Dis. 2018;12(4) - PMC - PubMed

[2] da Silva A.V.A., Figueiredo F.B. Morphophysiological changes in the splenic extracellular matrix of Leishmania infantum-naturally infected dogs is associated with alterations in lymphoid niches and the CD4+ T cell frequency in spleens. PLoS Negl Trop Dis. 2018;12(4) - PMC - PubMed

[3] Falqueto A., Ferreira A.L. Cross-sectional and longitudinal epidemiologic surveys of human and canine Leishmania infantum visceral infections in an endemic rural area of southeast Brazil (Pancas, Espirito Santo) Am J Trop Med Hyg. 2009;80(4):559–565. - PubMed

[4] Falqueto A., Ferreira A.L. Cross-sectional and longitudinal epidemiologic surveys of human and canine Leishmania infantum visceral infections in an endemic rural area of southeast Brazil (Pancas, Espirito Santo) Am J Trop Med Hyg. 2009;80(4):559–565. - PubMed

[5] Petersen C.A. Leishmaniasis, an emerging disease found in companion animals in the United States. Top Companion Anim Med. 2009;24(4):182–188. - PMC - PubMed

[6] Petersen C.A. Leishmaniasis, an emerging disease found in companion animals in the United States. Top Companion Anim Med. 2009;24(4):182–188. - PMC - PubMed

[7] Nieto A., Domínguez-Bernal G. Mechanisms of resistance and susceptibility to experimental visceral leishmaniosis: BALB/c mouse versus Syrian hamster model. Vet Res. 2011;42(1):39. - PMC - PubMed

[8] Nieto A., Domínguez-Bernal G. Mechanisms of resistance and susceptibility to experimental visceral leishmaniosis: BALB/c mouse versus Syrian hamster model. Vet Res. 2011;42(1):39. - PMC - PubMed

[9] Risso A. Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity. J Leukoc Biol. 2000;68(6):785–792. - PubMed

[10] Risso A. Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity. J Leukoc Biol. 2000;68(6):785–792. - PubMed

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Non-human primates and Leishmania immunity

Affiliations

Non-human primates and Leishmania immunity

Authors

Affiliations

Abstract

Conflict of interest statement

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