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. 2020 Oct 12;2(4):100038.
doi: 10.1016/j.cytox.2020.100038. eCollection 2020 Dec.

Non-human primates and Leishmania immunity

Sonia André  1 , Vasco Rodrigues  1 , Morgane Picard  1 , Ricardo Silvestre  2   3 , Jérôme Estaquier  1   4
Affiliations

Non-human primates and Leishmania immunity

Sonia André et al. Cytokine X. .

Abstract

In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus Leishmania and classified as one of the neglected tropical diseases.

Keywords: CXCR5; Cytokines; Immunity; Leishmania; Monkeys; T cells; Tfh.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Primate phylogeny.
See this image and copyright information in PMC

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