. 2021 May;48(5):1626-1638.

doi: 10.1007/s00259-021-05245-y. Epub 2021 Feb 19.

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Francesco Ceci¹, Daniela E Oprea-Lager², Louise Emmett^{3

4}, Judit A Adam⁵, Jamshed Bomanji⁶, Johannes Czernin⁷, Matthias Eiber⁸, Uwe Haberkorn⁹, Michael S Hofman^{10

11}, Thomas A Hope¹², Rakesh Kumar¹³, Steven P Rowe¹⁴, Sarah M Schwarzenboeck¹⁵, Stefano Fanti¹⁶, Ken Herrmann¹⁷

Affiliations

¹ Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.
² Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. d.oprea-lager@amsterdamumc.nl.
³ St. Vincent's Clinical School, University of New South Wales, Kensington, NSW, Australia.
⁴ Department of Theranostics and Nuclear Medicine, St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
⁵ Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
⁶ Department of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
⁷ Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.
⁸ School of Medicine, Department of Nuclear Medicine, Technische Universität München, Munich, Germany.
⁹ Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
¹⁰ Molecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
¹¹ Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia.
¹² Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
¹³ Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
¹⁴ Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
¹⁵ Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
¹⁶ Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy.
¹⁷ Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.

PMID: 33604691
PMCID: PMC8113168
DOI: 10.1007/s00259-021-05245-y

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Francesco Ceci et al. Eur J Nucl Med Mol Imaging. 2021 May.

. 2021 May;48(5):1626-1638.

doi: 10.1007/s00259-021-05245-y. Epub 2021 Feb 19.

Authors

Affiliations

¹ Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.
² Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. d.oprea-lager@amsterdamumc.nl.
³ St. Vincent's Clinical School, University of New South Wales, Kensington, NSW, Australia.
⁴ Department of Theranostics and Nuclear Medicine, St. Vincent's Hospital Sydney, Darlinghurst, NSW, Australia.
⁵ Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
⁶ Department of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
⁷ Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.
⁸ School of Medicine, Department of Nuclear Medicine, Technische Universität München, Munich, Germany.
⁹ Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
¹⁰ Molecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
¹¹ Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia.
¹² Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
¹³ Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
¹⁴ Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
¹⁵ Department of Nuclear Medicine, Rostock University Medical Centre, Rostock, Germany.
¹⁶ Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy.
¹⁷ Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.

PMID: 33604691
PMCID: PMC8113168
DOI: 10.1007/s00259-021-05245-y

Abstract

Rationale: The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician therapeutic management decisions.

Methods: A panel of worldwide experts in PSMA-PET was established. Panelists were selected based on their expertise and publication record in the diagnosis or treatment of PCa, in their involvement in clinical guidelines and according to their expertise in the clinical application of radiolabeled PSMA inhibitors. Panelists were actively involved in all stages of a modified, nonanonymous, Delphi consensus process.

Results: According to the findings obtained by modified Delphi consensus process, panelist recommendations were implemented in a structured report for PSMA-PET.

Conclusions: The E-PSMA standardized reporting guidelines, a document supported by the European Association of Nuclear Medicine (EANM), provide consensus statements among a panel of experts in PSMA-PET imaging, to develop a structured report for PSMA-PET in prostate cancer and to harmonize diagnostic interpretation criteria.

Keywords: Consensus panel; EANM guidelines; PSMA prostate cancer; PSMA-PET; Prostate cancer guidelines; Structured report.

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Conflict of interest statement

The authors declare no competing interests.

Figures

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Comment in

Lymph node classification in E‑PSMA reporting guidelines for PSMA‑PET.
Oprea-Lager DE, Ceci F, Eiber M, Fanti S, Herrmann K. Oprea-Lager DE, et al. Eur J Nucl Med Mol Imaging. 2022 Dec;50(1):10-11. doi: 10.1007/s00259-022-06007-0. Epub 2022 Oct 15. Eur J Nucl Med Mol Imaging. 2022. PMID: 36241913 No abstract available.

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E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Affiliations

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

Comment in

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Miscellaneous