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. 1988;16(1):46-8.
doi: 10.1007/BF01646932.

The role of staphylococcal lectins in human granulocyte stimulation

J Beuth  1 , H L Ko, G Pulverer
Affiliations

The role of staphylococcal lectins in human granulocyte stimulation

J Beuth et al. Infection. 1988.

Abstract

The anti-staphylococcal activity spectrum of human polymorphonuclear leucocytes (PMN) is widely ranged. Using chemiluminescence measurements, the opsonin-independent stimulation of PMNs from eight healthy humans towards two Staphylococcus saprophyticus strains (S 1 and S 35) was investigated. Strain S 1 was shown to have surface lectins with N-acetylgalactosamine specificity, whereas strain S 35 had N-acetyl-neuraminic acid specificity. Three different PMN-reaction patterns could be demonstrated: PMN stimulation was either sensitive to N-acetylgalactosamine-or N-acetylneuraminic acid-blocking, or resistant to both. These results point to the importance of lectins for staphylococcal-PMN interactions.

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References

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