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. 2021 Sep;59(9):843-845.
doi: 10.1080/15563650.2021.1887492. Epub 2021 Feb 19.

Intravenous rifampicin use in the management of amanita phalloides toxicity

Rona Zuker-Herman  1 , Roger Tong  1 , Anselm Wong  2
Affiliations

Intravenous rifampicin use in the management of amanita phalloides toxicity

Rona Zuker-Herman et al. Clin Toxicol (Phila). 2021 Sep.

Abstract

Context: Amanita phalloides related toxicity from amatoxins can result in acute liver and multi-organ failure and is responsible for 90% of all mushroom poisoning death. However, more evidence is needed in regards to different management strategies.Case details: We present two cases of amanita mushroom ingestion who were treated with intravenous rifampicin.Discussion: Further study is needed to establish the efficacy and role of rifampicin in amatoxin related mushroom poisoning.

Keywords: Liver; antimicrobials; gut and hepatotoxicity; other.

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