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Comment
. 2021 Jul;41(5):926-929.
doi: 10.1007/s10875-021-00996-7. Epub 2021 Feb 20.

Resolution of Persistent COVID-19 After Convalescent Plasma in a Patient with B Cell Aplasia

Affiliations
Comment

Resolution of Persistent COVID-19 After Convalescent Plasma in a Patient with B Cell Aplasia

Emily McKemey et al. J Clin Immunol. 2021 Jul.

Erratum in

No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
a Serial serum IgG (gray), IgA (blue), and IgM (red) measurements over time. Normal ranges are shown by dotted lines. Asterisk “*” represents date rituximab was initiated. b Changes in peripheral blood neutrophil count, lymphocyte count, C-reactive protein, and temperature over the time course of disease relative to pharmacological treatments received. Time course is relative to the first presentation on 16/4/2020. c Level of serum IgG, IgA, and IgM anti-SARS-CoV-2 trimeric spike glycoprotein antibodies were measured before and after treatment with convalescent plasma. Results are expressed as a signal to the cutoff calibrator ratio with the dotted line representing the cutoff for positivity. d In vitro SARS-CoV-2 neutralizing activity of serum from the patient before (day 91) and after (day 106 and day 119) the administration of convalescent plasma. Dex, dexamethasone; PCR, polymerase chain reaction; CT, cycle threshold; TMA, transcription-mediated amplification

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