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. 2020 Dec;12(6):625-628.
doi: 10.18502/ijm.v12i6.5038.

The gender differences as a risk factor in diabetic patients with COVID-19

Tahir Belice  1 , Ismail Demir  1
Affiliations

The gender differences as a risk factor in diabetic patients with COVID-19

Tahir Belice et al. Iran J Microbiol. 2020 Dec.

Abstract

Background and objectives: In a Turkish cohort study, we revealed first time in literature the gender differences in admission to hospital and rates of mortality for diabetic patients with COVID-19.

Materials and methods: The demographics, length of stay, mortality rates and concomitant chronic metabolic diseases of 152 patients diagnosed with COVID-19 were found in our hospital electronic document system (Probel) and recorded in excel files for further statistical analysis.

Results: In the mortality group (n:22), the numbers of men and women were 9 (40.9%) and 4 (18.2%), respectively. Comparing gender rates in diabetic group, the mortality risk of diabetic men was higher and statistically significant (p<0.05, Pearson Chi-square value:7.246).

Conclusion: We hope that the findings of this research will give scientists an idea of gender differences in viral pandemics for further studies.

Keywords: COVID-19; Diabetes mellitus type 2; Sex factors.

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References

    1. Moutschen MP, Scheen AJ, Lefebvre PJ. Impaired immune responses in diabetes mellitus: analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections. Diabete Metab 1992;18:187–201. - PubMed
    1. Knapp S. Diabetes and infection: is there a link?--A mini-review. Gerontology 2013;59:99–104. - PubMed
    1. Ilyas R, Wallis R, Soilleux EJ, Townsend P, Zehnder D, Tan BK, et al. High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus. Immunobiology 2010;216:126–131. - PMC - PubMed
    1. Li L, Liu Y, Wu P, Peng Z, Wang X, Chen T, et al. Influenza-associated excess respiratory mortality in China, 2010–15: a population-based study. Lancet Public Health 2019; 4(9):e473–e481. - PMC - PubMed
    1. Wang A, Zhao W, Xu Z, Gu J. Timely blood glucose management for the outbreak of 2019 novel coronavirus disease (COVID-19) is urgently needed. Diabetes Res Clin Pract 2020;162:108118. - PMC - PubMed

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