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Case Reports
. 2021 Jan;7(1):50-53.
doi: 10.1159/000510857. Epub 2020 Oct 26.

Subungual Elastofibroma

Eckart Haneke  1   2   3
Affiliations
Case Reports

Subungual Elastofibroma

Eckart Haneke. Skin Appendage Disord. 2021 Jan.

Abstract

Cutaneous elastofibroma is part of the connective tissue nevus complex. Two subungual cases remotely similar to the one presented here have been described before. This patient presented with an unusual form of subungual elastofibroma of the big toe, which was surgically removed. Histopathology revealed a connective tissue tumor extremely rich in very fine elastic fibers. Their relationship to oxytalan and elaunin fibers is discussed as is the potential association of this nail bed lesion with the onychodermis.

Keywords: Connective tissue nevi; Nail tumors; Onychodermis; Onychopathology; Subungual elastofibroma.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1
Subungual elastofibroma. The left big toenail is yellow, thickened, intransparent, overcurved, and onycholytic. Both big toes show a moderate hallux valgus interphalangeus.
Fig. 2
Fig. 2
Subungual elastofibroma. Directly after cutting the onycholytic nail away, a disappeared nail bed and a pronounced distal bulge impeding normal nail growth are seen.
Fig. 3
Fig. 3
Subungual elastofibroma. After reflection of the nail, a slight bulging of the nail bed is visible.
Fig. 4
Fig. 4
Subungual elastofibroma. Histopathology of the H&E sections. High magnification reveals dense eosinophilic collagen with many fibroblasts that display angulated to stellate nuclei without atypia. H&E, ×200.
Fig. 5
Fig. 5
Subungual elastofibroma. Weigert's elastic stain reveals abundant fine elastic fibers. a Marked increase in fine and wavy elastic fibers. b Concentration of fine elastic fibers. Weigert's elastic stain. ×400 (a), ×200 (b).
Fig. 6
Fig. 6
Subungual elastofibroma. Immunohistochemical demonstration of CD10. CD10 is strongly and diffusely demonstrated in the tumor. CD10, ×100.
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