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. 2021 Feb 15;7(1):00723-2020.
doi: 10.1183/23120541.00723-2020. eCollection 2021 Jan.

Conditional expanding post-exposure prophylaxis: a potential new tool for tuberculosis control

Affiliations

Conditional expanding post-exposure prophylaxis: a potential new tool for tuberculosis control

Henan Xin et al. ERJ Open Res. .

Abstract

For individuals with high risk of exposure and thereafter developing and transmitting active tuberculosis, conditional post-exposure prophylaxis might be a potential tool for tuberculosis control https://bit.ly/39qHHh4.

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Conflict of interest statement

Conflict of interest: H. Xin has nothing to disclose. Conflict of interest: Q. Jin has nothing to disclose. Conflict of interest: L. Gao has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Building a risk evaluation system for individuals with Mycobacterium tuberculosis (MTB) exposure. For individuals with confirmed MTB exposure, a risk grading system should be built according to their risks of infection after exposure, risks of disease development from infection and risks of transmission after disease occurrence. For those with high grades of risks, post-exposure prophylaxis might be administrated regardless of tuberculosis (TB) infection testing results. For those with medium risks, priorities for preventative treatment should be given to those with positive TB infection testing results. While for those with low risks, regular evaluation and follow-up might be suggested.

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References

    1. WHO. WHO consolidated guidelines on tuberculosis: module 1: prevention: tuberculosis preventive treatment. Geneva, World Health Organization, 2020. www.who.int/publications-detail/who-consolidated-guidelines-on-tuberculo... Date last accessed 24 March 2020. - PubMed
    1. Eakle R, Venter F, Rees H. Pre-exposure prophylaxis (PrEP) in an era of stalled HIV prevention: Can it change the game? Retrovirology 2018; 15: 29. doi:10.1186/s12977-018-0408-3 - DOI - PMC - PubMed
    1. WHO. Global strategy and targets for tuberculosis prevention, care and control after 2015 www.who.int/tb/post2015_tbstrategy.pdf?ua=1 Date last accessed May 2016. Date last updated: December 2013.
    1. Getahun H, Matteelli A, Chaisson RE, et al. . Latent Mycobacterium tuberculosis infection. N Engl J Med 2015; 372: 2127–2135. doi:10.1056/NEJMra1405427 - DOI - PubMed
    1. Saunders MJ, Wingfield T, Datta S, et al. . A household-level score to predict the risk of tuberculosis among contacts of patients with tuberculosis: a derivation and external validation prospective cohort study. Lancet Infect Dis 2020; 20: 110–122. doi:10.1016/S1473-3099(19)30423-2 - DOI - PMC - PubMed

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