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. 2021 Feb 12;6(1):1-4.
doi: 10.1089/can.2020.0027. eCollection 2021.

Chirality in Cannabinoid Research

Crist N Filer  1
Affiliations

Chirality in Cannabinoid Research

Crist N Filer. Cannabis Cannabinoid Res. .

Abstract

Mankind has long utilized Cannabis for diverse purposes. However, it has only been since the late 19th century that its individual cannabinoids began to be isolated, analyzed, and synthesized. By the mid-20th century it was discovered that many cannabinoids were asymmetric, with chirality often controlling their pharmacology. Increasingly accurate measurement and understanding of cannabinoid chirality will facilitate their synthesis and accelerate their medicinal applications.

Keywords: MicroED; cannabinoid; cannabis; chiral HPLC.

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Conflict of interest statement

No competing financial interests exist.

Figures

FIG. 1.
FIG. 1.
Structures of cannabinol (1), cannabidiol (2), delta-9-tetrahydrocannabinol (3), and cannabichromene (4).
See this image and copyright information in PMC

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