Meta-analysis of the Effect of Colchicine on Mortality and Mechanical Ventilation in COVID-19
- PMID: 33617817
- PMCID: PMC7894200
- DOI: 10.1016/j.amjcard.2021.02.005
Meta-analysis of the Effect of Colchicine on Mortality and Mechanical Ventilation in COVID-19
Conflict of interest statement
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Figures


Similar articles
-
Effect of Colchicine vs Usual Care Alone on Intubation and 28-Day Mortality in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.JAMA Netw Open. 2021 Dec 1;4(12):e2141328. doi: 10.1001/jamanetworkopen.2021.41328. JAMA Netw Open. 2021. PMID: 34964849 Free PMC article. Clinical Trial.
-
Case Fatality Rates for Patients with COVID-19 Requiring Invasive Mechanical Ventilation. A Meta-analysis.Am J Respir Crit Care Med. 2021 Jan 1;203(1):54-66. doi: 10.1164/rccm.202006-2405OC. Am J Respir Crit Care Med. 2021. PMID: 33119402 Free PMC article. Review.
-
Can we still consider treatment with colchicine effective in SARS-COV-2 infection? Systematic review, meta-analysis, and trial sequential analysis.Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):7151-7161. doi: 10.26355/eurrev_202111_27269. Eur Rev Med Pharmacol Sci. 2021. PMID: 34859881
-
Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes.Am J Cardiovasc Drugs. 2021 Sep;21(5):499-512. doi: 10.1007/s40256-020-00459-1. Epub 2020 Dec 28. Am J Cardiovasc Drugs. 2021. PMID: 33369719 Free PMC article. Review.
-
Colchicine use in patients with COVID-19: A systematic review and meta-analysis.PLoS One. 2021 Dec 28;16(12):e0261358. doi: 10.1371/journal.pone.0261358. eCollection 2021. PLoS One. 2021. PMID: 34962939 Free PMC article.
Cited by
-
Colchicine Against SARS-CoV-2 Infection: What is the Evidence?Rheumatol Ther. 2022 Apr;9(2):379-389. doi: 10.1007/s40744-022-00425-0. Epub 2022 Feb 2. Rheumatol Ther. 2022. PMID: 35107804 Free PMC article. Review.
-
Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation.Inflamm Res. 2022 Mar;71(3):293-307. doi: 10.1007/s00011-022-01540-y. Epub 2022 Feb 3. Inflamm Res. 2022. PMID: 35113170 Free PMC article. Review.
-
Therapeutic role of immunomodulators during the COVID-19 pandemic- a narrative review.Postgrad Med. 2022 Mar;134(2):160-179. doi: 10.1080/00325481.2022.2033563. Epub 2022 Feb 12. Postgrad Med. 2022. PMID: 35086413 Free PMC article. Review.
-
Efficacy and safety of colchicine in COVID-19: a meta-analysis of randomised controlled trials.RMD Open. 2021 Oct;7(3):e001746. doi: 10.1136/rmdopen-2021-001746. RMD Open. 2021. PMID: 34810227 Free PMC article.
-
A Multidisciplinary Approach to Coronavirus Disease (COVID-19).Molecules. 2021 Jun 9;26(12):3526. doi: 10.3390/molecules26123526. Molecules. 2021. PMID: 34207756 Free PMC article. Review.
References
-
- Richter M, Boldescu V, Graf D, Streicher F, Dimoglo A, Bartenschlager R, Klein CD. Synthesis, biological evaluation, and molecular docking of combretastatin and colchicine derivatives and their hCE1-activated prodrugs as antiviral agents. ChemMedChem. 2019;14:469–483. - PubMed
-
- Deftereos SG, Giannopoulos G, Vrachatis DA, Siasos GD, Giotaki SG, Gargalianos P, Metallidis S, Sianos G, Baltagiannis S, Panagopoulos P, Dolianitis K, Randou E, Syrigos K, Kotanidou A, Koulouris NG, Milionis H, Sipsas N, Gogos C, Tsoukalas G, Olympios CD, Tsagalou E, Migdalis I, Gerakari S, Angelidis C, Alexopoulos D, Davlouros P, Hahalis G, Kanonidis I, Katritsis D, Kolettis T, Manolis AS, Michalis L, Naka KK, Pyrgakis VN, Toutouzas KP, Triposkiadis F, Tsioufis K, Vavouranakis E, Martinèz-Dolz L, Reimers B, Stefanini GG, Cleman M, Goudevenos J, Tsiodras S, Tousoulis D, Iliodromitis E, Mehran R, Dangas G, Stefanadis C. Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019: the GRECCO-19 randomized clinical trial. JAMA Netw Open. 2020;3 - PMC - PubMed
-
- Vrachatis DA, Giannopoulos GV, Giotaki SG, Raisakis K, Kossyvakis C, Iliodromitis KE, Reimers B, Tousoulis D, Cleman M, Stefanadis C, Lansky A, Deftereos SG. Impact of colchicine on mortality in patients with COVID-19. A meta-analysis. Hellenic J Cardiol. 2021 Jan 6 [published online ahead of print] - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical