Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Aug:235:264-276.e1.
doi: 10.1016/j.jpeds.2021.02.026. Epub 2021 Feb 20.

Acetaminophen and the Developing Lung: Could There Be Lifelong Consequences?

Affiliations
Review

Acetaminophen and the Developing Lung: Could There Be Lifelong Consequences?

Clyde J Wright. J Pediatr. 2021 Aug.
No abstract available

Keywords: acetaminophen; bronchopulmonary dysplasia; newborn; outcomes; paracetamol.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Number of manuscripts identified with the search “acetaminoph* OR paracetam* AND ductus arteriosus from 2011 to 2020.
Figure 2.
Figure 2.
APAP metabolism. GSH, glutathione.
Figure 3.
Figure 3.
Difference in BPD incidence plotted against average gestational age of enrolled subjects. Below the x-axis represents the BPD incidence in % lower vs the control group. Above the x-axis represents the BPD incidence in % higher vs the control group. Each point is an individual study, labeled with first author and year published. GA, gestational age.–,–,,

Similar articles

Cited by

References

    1. Hsieh EM, Hornik CP, Clark RH, Laughon MM, Benjamin DK Jr, Smith PB, et al. Medication use in the neonatal intensive care unit. Am J Perinatol 2014;31:811–21. - PMC - PubMed
    1. Mehler K, Oberthuer A, Haertel C, Herting E, Roth B, Goepel W, et al. Use of analgesic and sedative drugs in VLBW infants in German NICUs from 2003-2010. Eur J Pediatr 2013;172:1633–9. - PubMed
    1. Gouyon B, Martin-Mons S, Iacobelli S, Razafimahefa H, Kermorvant-Duchemin E, Brat R, et al. Characteristics of prescription in 29 Level 3 Neonatal Wards over a 2-year period (2017-2018). An inventory for future research. PLoS One 2019;14:e0222667. - PMC - PubMed
    1. Benahmed-Canat A, Plaisant F, Riche B, Rabilloud M, Canat G, Paret N, et al. Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: a single-center retrospective cohort study. Arch Pediatr 2019;26:145–50. - PubMed
    1. Allegaert K. A Critical review on the relevance of paracetamol for procedural pain management in neonates. Front Pediatr 2020;8:89. - PMC - PubMed

MeSH terms