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. 2021 Feb 22;11(1):4328.
doi: 10.1038/s41598-021-82262-9.

Laparoscopic isolated caudate lobe resection

Maulik Parikh  1 , Ho-Seong Han  2 , Jai Young Cho  3 , Mizelle D'Silva  3
Affiliations

Laparoscopic isolated caudate lobe resection

Maulik Parikh et al. Sci Rep. .

Erratum in

Abstract

Previously, isolated caudate lobectomy was rarely performed and the caudate lobe was usually resected along with other segments. Isolated caudate lobe resection is a challenging procedure even for an experienced surgeon. Our aim was to evaluate the feasibility, safety and outcomes of laparoscopic isolated caudate lobectomy and to compare these with the open technique. We retrospectively analyzed 21 patients who underwent isolated caudate lobectomy between January 2005 and December 2018 at Seoul National University Bundang Hospital. Patients who underwent either anatomical or non-anatomical resection of the caudate lobe were included. Patients were divided into two groups according to whether they underwent laparoscopic or open surgery. Intra-operative and postoperative outcomes were compared with a median follow-up of 43 months (4-149). A total of 21 patients were included in the study. Of these, 12 (57.14%) underwent laparoscopic and nine (42.85%) underwent open caudate lobectomy. Median operation time (204.5 vs. 200 minutes, p = 0.397), estimated blood loss (250 vs. 400 ml, p = 0.214) and hospital stay (4 vs. 7 days, p = 0.298) were comparable between laparoscopy and open group. The overall post operative complication rate was similar in both groups (p = 0.375). The 5-year disease free survival rate (42.9% vs 60.0%, p = 0.700) and the 5-year overall survival rate (76.2% vs 64.8%, p = 0.145) was similar between laparoscopy and open group. Our findings demonstrate that with increasing surgical expertise and technological advances, laparoscopic isolated caudate lobectomy can become a feasible and safe in selected patients.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Anatomy of the caudate lobe. HV hepatic vein, PV portal vein, IVC inferior vena cava.
Figure 2
Figure 2
Technical aspect of laparoscopic caudate lobectomy. (a) The right posterior glissonian pedicle was isolated and temporarily clamped. (b) The caudate glissonian branches were identified and controlled. (c) The exposure of right hepatic vein. (d) After complete resection of caudate lobe, the exposure of middle hepatic vein.
Figure 3
Figure 3
Photos taken from laparoscopic caudate lobectomy (a) The right posterior glissonian pedicle was isolated and temporarily clamped. (b) The caudate glissonian branches were identified and controlled. (c The exposure of right hepatic vein. (d) After complete resection of caudate lobe, the exposure of middle hepatic vein.
Figure 4
Figure 4
Kaplan–Meier plot of disease-free survival.
Figure 5
Figure 5
Kaplan–Meier plot of overall survival.
See this image and copyright information in PMC

References

    1. Philips P, Farmer RW, Scoggins CR, McMasters KM, Martin RCG., 2nd Caudate lobe resections: A single-center experience and evaluation of factors predictive of outcomes. World J. SurgOncol. 2013;11:220. - PMC - PubMed
    1. Feng X, Hu Y, Peng J, Liu A, Tian L, et al. A left-sided approach for resection of hepatic caudate lobe hemangioma: two case reports and a literature review. Int. Surg. 2015;100:1054–1059. doi: 10.9738/INTSURG-D-14-00317.1. - DOI - PMC - PubMed
    1. Fernandes EdSM, Pacilio CA, de Mello FPT, de Oliveira Andrade R, Pimentel LMS et al. Anterior transhepatic approach for total caudate lobectomy including spigelian lobe, paracaval portion and caudate process: A Brazilian experience. Hepatobiliary Pancreat Dis Int ; 17: 371–3 (2018). - PubMed
    1. Liu P, Qiu B-A, Bai G, Bai H-W, Xia N-X, et al. Choice of approach for hepatectomy for hepatocellular carcinoma located in the caudate lobe: isolated or combined lobectomy? World J. Gastroenterol. 2012;18:3904–3909. doi: 10.3748/wjg.v18.i29.3904. - DOI - PMC - PubMed
    1. Peng SY, Liu YB, Wang JW, Li JT, Liu FB, et al. Retrograde Resection of caudate lobe of liver. J. Am. Coll. Surg. 2008;206:1232–1238. doi: 10.1016/j.jamcollsurg.2007.11.013. - DOI - PubMed

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