Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2021 Jun 4;22(6):1435-1440.
doi: 10.1093/pm/pnab072.

Herbal Topical Analgesic for Pain Management: Perspectives from Cancer Patients

Affiliations
Randomized Controlled Trial

Herbal Topical Analgesic for Pain Management: Perspectives from Cancer Patients

Kevin T Liou et al. Pain Med. .

Abstract

Objective: Herbs and natural products are increasingly used by cancer patients for pain management, but few studies have examined their integration within conventional cancer care. This study describes the characteristics, experiences, and perspectives of cancer patients who were prescribed an herbal topical analgesic for pain management.

Design and setting: Program evaluation of a pilot herbal dispensary at a National Cancer Institute-designated comprehensive cancer center.

Subjects: Cancer patients who were prescribed the Tibetree Pain-Relieving Plaster (PRP) by an integrative medicine physician.

Methods: Sociodemographic and clinical characteristics of patients were abstracted from medical records. Semistructured phone interviews were conducted 1-2 weeks after PRP prescription to evaluate patient experiences with using PRP for pain. Interviews were analyzed through thematic content analysis.

Results: From February 2019 to February 2020, 50 patients were prescribed PRP. Median age (range) was 63 years (21-86), 37 patients (74%) were female, 14 (28%) were non-White, and 38 (76%) were using oral analgesics. During interviews, the majority of patients reported that the PRP improved pain and health-related outcomes, was convenient to use, and addressed pain management needs that were not fulfilled by oral analgesics. However, a few patients described adverse experiences with PRP, including skin irritation.

Conclusions: Understanding patient experiences and perspectives is a critical step toward evidence-based integration of herbs and natural products into cancer pain management. Findings from this program evaluation will inform the design of a randomized clinical trial on the efficacy and safety of PRP for pain in patients with cancer.

Keywords: Cancer; Herbs; Integrative Medicine; Natural Products; Pain Management.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Miller KD, Nogueira L, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2019. CA: Cancer J Clin 2019;69(5):363–85. - PubMed
    1. Siegel RL, Miller KD, Jemal A.. Cancer statistics, 2019. CA: Cancer J Clin 2019;69(1):7–34. - PubMed
    1. van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, et al. Prevalence of pain in patients with cancer: A systematic review of the past 40 years. Ann Oncol 2007;18(9):1437–49. - PubMed
    1. van den Beuken-van Everdingen MH, Hochstenbach LM, Joosten EA, Tjan-Heijnen VC, Janssen DJ.. Update on prevalence of pain in patients with cancer: Systematic review and meta-analysis. J Pain Symptom Manag 2016;51(6):1070–90.e9. - PubMed
    1. Zylla D, Steele G, Gupta P.. A systematic review of the impact of pain on overall survival in patients with cancer. Support Care Cancer 2017;25(5):1687–98. - PubMed

Publication types