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. 2021 Mar;27(3):985-987.
doi: 10.3201/eid2703.204418.

Limited Capability for Testing Mycobacterium tuberculosis for Susceptibility to New Drugs

Hamzah Z Farooq, Daniela M Cirillo, Doris Hillemann, David Wyllie, Marieke J van der Werf, Csaba Ködmön, Vlad Nikolayevskyy

Limited Capability for Testing Mycobacterium tuberculosis for Susceptibility to New Drugs

Hamzah Z Farooq et al. Emerg Infect Dis. 2021 Mar.

Abstract

We surveyed availability of phenotypic drug susceptibility testing for drug-resistant Mycobacterium tuberculosis in Europe. Of 27 laboratories, 17 tested for linezolid, 11 for clofazimine, 9 for bedaquiline, and 6 for delamanid during 2019. Our findings indicate that testing capacity for newer and repurposed tuberculosis drugs exists, but its availability is limited.

Keywords: Europe; Mycobacterium tuberculosis; antimicrobial resistance; bacteria; drug susceptibility; drugs; public health; respiratory infections; testing; tuberculosis; tuberculosis and other mycobacteria.

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Figures

Figure
Figure
European Union laboratories performing phenotypic DST of new tuberculosis drugs, 2019. Map courtesy of Mapbox OpenStreet Map (https://www.mapbox.com). DST, drug susceptibility testing.
See this image and copyright information in PMC

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