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Editorial
. 2021 Apr;124(8):1341-1343.
doi: 10.1038/s41416-021-01265-5. Epub 2021 Feb 24.

Cannabinoids in glioblastoma multiforme-hype or hope?

Gary J Doherty  1   2 , Bruno H R de Paula  3   4   5
Affiliations
Editorial

Cannabinoids in glioblastoma multiforme-hype or hope?

Gary J Doherty et al. Br J Cancer. 2021 Apr.

Erratum in

  • Publisher Correction.
    [No authors listed] [No authors listed] Br J Cancer. 2021 Oct;125(8):1177. doi: 10.1038/s41416-021-01520-9. Br J Cancer. 2021. PMID: 34417578 Free PMC article. No abstract available.

Abstract

Cannabis and its derivatives are being used increasingly by patients with cancer, including patients with glioblastoma multiforme (GBM), the most common and aggressive primary brain malignancy. Despite promising preclinical data suggesting potential anti-cancer effects for cannabinoids in GBM, clinical and safety data are lacking. This editorial will discuss a recent Phase 1b trial of nabiximols oromucosal spray in combination with dose-intense temozolomide in patients with recurrent GBM in the context of other relevant findings in this field.

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Conflict of interest statement

The authors declare no competing interests.

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