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. 2021 Apr;21(4):202-203.
doi: 10.1038/s41577-021-00516-z.

SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship

Chrysanthi Skevaki  1   2 , Antonina Karsonova  3 , Alexander Karaulov  3 , Daria Fomina  3   4 , Min Xie  5 , Sharon Chinthrajah  6 , Kari C Nadeau  6 , Harald Renz  7   8   9
Affiliations

SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship

Chrysanthi Skevaki et al. Nat Rev Immunol. 2021 Apr.

Abstract

Risk of severe coronavirus disease 2019 (COVID-19) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increased in patients with certain comorbidities, including chronic obstructive pulmonary disease (COPD). By contrast, epidemiological data from many (but not all) countries indicate a low prevalence of asthma among patients with severe COVID-19. This reduced risk of severe COVID-19 may apply specifically to patients with the type 2 asthma endotype, which is most common in childhood asthma.

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Conflict of interest statement

C.S. has received consultancy fees and/or funding from Hycor Biomedical, Thermo Fisher Scientific, Mead Johnson Nutrition (MJN) and Bencard Allergie. H.R. has received consultancy fees from Roche Diagnostics, Hycor Biomedical, Allergopharma, Novartis, Thermo Fisher Scientific, Danone, MJN, Bencard, Nutricia and Nestlé. D.F. has received consultancy fees and funding from Novartis, Sanofi, Takeda (Shire), CSL Behring, GlaxoSmithKline, AstraZeneca and Pfizer. The other authors declare no competing interests.

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