Finding function with base editing screens

Affiliations

Comment

Linda Koch. Nat Rev Genet. 2021 Apr.

. 2021 Apr;22(4):200-201.

doi: 10.1038/s41576-021-00340-0.

No abstract available

Comment on

Massively parallel assessment of human variants with base editor screens.
Hanna RE, Hegde M, Fagre CR, DeWeirdt PC, Sangree AK, Szegletes Z, Griffith A, Feeley MN, Sanson KR, Baidi Y, Koblan LW, Liu DR, Neal JT, Doench JG. Hanna RE, et al. Cell. 2021 Feb 18;184(4):1064-1080.e20. doi: 10.1016/j.cell.2021.01.012. Cell. 2021. PMID: 33606977
Functional interrogation of DNA damage response variants with base editing screens.
Cuella-Martin R, Hayward SB, Fan X, Chen X, Huang JW, Taglialatela A, Leuzzi G, Zhao J, Rabadan R, Lu C, Shen Y, Ciccia A. Cuella-Martin R, et al. Cell. 2021 Feb 18;184(4):1081-1097.e19. doi: 10.1016/j.cell.2021.01.041. Cell. 2021. PMID: 33606978 Free PMC article.

1. Hanna, R. E. et al. Massively parallel assessment of human variants with base editor screens. Cell 184, 1064–1080 (2021) - DOI
1. Cuella-Martin, R. et al. Functional interrogation of DNA damage response variants with base editing screens. Cell 184, 1081–1097 (2021) - DOI