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. 2021 Aug 2;73(3):e826-e829.
doi: 10.1093/cid/ciab103.

Patients With Uncomplicated Coronavirus Disease 2019 (COVID-19) Have Long-Term Persistent Symptoms and Functional Impairment Similar to Patients with Severe COVID-19: A Cautionary Tale During a Global Pandemic

Karen B Jacobson  1 , Mallika Rao  2 , Hector Bonilla  1 , Aruna Subramanian  1 , Isabelle Hack  2 , Martina Madrigal  2 , Upinder Singh  1   3 , Prasanna Jagannathan  1   3 , Philip Grant  1
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Patients With Uncomplicated Coronavirus Disease 2019 (COVID-19) Have Long-Term Persistent Symptoms and Functional Impairment Similar to Patients with Severe COVID-19: A Cautionary Tale During a Global Pandemic

Karen B Jacobson et al. Clin Infect Dis. .

Abstract

To assess the prevalence of persistent functional impairment after coronavirus disease (COVID-19), we assessed 118 individuals 3-4 months after their initial COVID-19 diagnosis with a symptom survey, work productivity and activity index questionnaire, and 6-minute walk test. We found significant persistent symptoms and functional impairment, even in non-hospitalized patients with COVID-19.

Trial registration: ClinicalTrials.gov NCT04331899 NCT04346628 NCT04292899.

Keywords: COVID-19; COVID-19 symptoms; Long COVID; SARS-CoV-2; functional impairment.

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