Comment on

• Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition.

  Tang PM, Zhang YY, Xiao J, Tang PC, Chung JY, Li J, Xue VW, Huang XR, Chong CC, Ng CF, Lee TL, To KF, Nikolic-Paterson DJ, Lan HY. Tang PM, et al. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20741-20752. doi: 10.1073/pnas.1917663117. Epub 2020 Aug 11. Proc Natl Acad Sci U S A. 2020. PMID: 32788346 Free PMC article.
• Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

  Vatapalli R, Sagar V, Rodriguez Y, Zhao JC, Unno K, Pamarthy S, Lysy B, Anker J, Han H, Yoo YA, Truica M, Chalmers ZR, Giles F, Yu J, Chakravarti D, Carneiro B, Abdulkadir SA. Vatapalli R, et al. Nat Commun. 2020 Aug 19;11(1):4153. doi: 10.1038/s41467-020-18013-7. Nat Commun. 2020. PMID: 32814769 Free PMC article.
• Extensive heterogeneity in somatic mutation and selection in the human bladder.

  Lawson ARJ, Abascal F, Coorens THH, Hooks Y, O'Neill L, Latimer C, Raine K, Sanders MA, Warren AY, Mahbubani KTA, Bareham B, Butler TM, Harvey LMR, Cagan A, Menzies A, Moore L, Colquhoun AJ, Turner W, Thomas B, Gnanapragasam V, Williams N, Rassl DM, Vöhringer H, Zumalave S, Nangalia J, Tubío JMC, Gerstung M, Saeb-Parsy K, Stratton MR, Campbell PJ, Mitchell TJ, Martincorena I. Lawson ARJ, et al. Science. 2020 Oct 2;370(6512):75-82. doi: 10.1126/science.aba8347. Science. 2020. PMID: 33004514