Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Feb 12:2021:6684806.
doi: 10.1155/2021/6684806. eCollection 2021.

Gastroduodenal Ulcerative Colitis in Association with Ulcerative Pancolitis

Khin San Aye  1 , Lin Lin Htun  2 , Thet Mar Win  1 , Mya Thida Aye  1 , Drmyothettin Tin  3 , Than Than Aye  1
Affiliations
Case Reports

Gastroduodenal Ulcerative Colitis in Association with Ulcerative Pancolitis

Khin San Aye et al. Case Rep Gastrointest Med. .

Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, traditionally regarded as being limited to the colorectum. Although several gastroduodenal lesions have been reported in cases of UC, in general, duodenal lesions in UC are believed to be uncommon and gastric lesions in UC are a rare presentation. In this report, we presented a 66-year-old lady with upper GI presentation with gastroduodenal ulcerative colitis accompanying pancolonic UC.

PubMed Disclaimer

Conflict of interest statement

All the authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
EGD scopy findings; panulcerative gastritis and ulcerative duodenitis. (a) Antrum, (b) fundus, (c) proximal body stomach, and (d) descending part of the duodenum.
Figure 2
Figure 2
Colonoscopy findings; pancolitis with inflammatory polyps. (a) Rectum, (b) ascending colon, (c) caecum, and (d) terminal ileum.
Figure 3
Figure 3
Histologic findings of gastric biopsy; the gastric mucosa shows (a) severe inflammation, ulcerations, and architecture changes, (b) plasmacytosis in the lamina propria, (c) inflammation in the gastric foveolar epithelium, and (d) microabscess formations.
Figure 4
Figure 4
Histologic findings of duodenal biopsy; the duodenum mucosa shows (a) villous atrophy, architecture changes, and edematous lamina propria, (b) plasma cells (black arrow), and (c) cryptitis (blue arrow) in the lamina propria.
Figure 5
Figure 5
Histologic findings of colon biopsy; all pieces of the colonic polyps show (a) edematous lamina propria, crypt dropout, and mononuclear infiltrates, (b) crypts lined by reactive columnar cells, and (c) bacterial colonies.
Figure 6
Figure 6
Plain X-ray abdomen; gas under diaphragm positive, gas-filled distended stomach, and some bowel loops.
See this image and copyright information in PMC

References

    1. Grossman A. B., Baldassano R. N., Kligman R. M., et al. Chronic Ulcerative Colitis Nelson Textbook of Pediatrics. 19th. Philadelphia, PA, USA: W B Saunders; 2011.
    1. Jang E. S., Lee D. H., Kim J., et al. Age as a clinical predictor of relapse after induction therapy in ulcerative colitis. Hepatogastro-Enterology. 2009;56(94-95):1304–1309. - PubMed
    1. Diefenback K. A., Breuer C. K. Pediatric inflammatory bowel disease. World Journal of Gastroenterology. 2006;12:3204–3212. - PMC - PubMed
    1. Banerjee R., Pal P., Hilmi I., et al. IBD demographics in Southern Asia. Hyderabad, Telangana: IBD-ENC; 2019.
    1. Hori K., Ikeuchi H., Nakano H., et al. Gastroduodenitis associated with ulcerative colitis. Journal of Gastroenterology. 2008;43(3):193–201. doi: 10.1007/s00535-007-2143-8. - DOI - PubMed

Publication types

LinkOut - more resources