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. 2021 Jan 7;8(2):ofab002.
doi: 10.1093/ofid/ofab002. eCollection 2021 Feb.

Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette  1 , Sara Alosaimy  1 , Julie V Philley  2 , Carly Wadle  2 , Catessa Howard  3 , Andrew J Webb  4   5 , Michael P Veve  6   7 , Melissa L Barger  8 , Jeannette Bouchard  9 , Tristan W Gore  9 , Abdalhamid M Lagnf  1 , Iman Ansari  1 , Carlos Mejia-Chew  10 , Keira A Cohen  11 , Michael J Rybak  1   12   13
Affiliations

Preliminary, Real-world, Multicenter Experience With Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette et al. Open Forum Infect Dis. .

Abstract

Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2-11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy.

Keywords: Mycobacterium abscessus; omadacycline; rapidly growing nontuberculous mycobacteria.

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