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. 2021 Apr 1;134(4):509-514.
doi: 10.1097/ALN.0000000000003705.

Opioid-free Anesthesia: Time to Regain Our Balance

Evan D Kharasch, J David Clark

Opioid-free Anesthesia: Time to Regain Our Balance

Evan D Kharasch et al. Anesthesiology. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Dr. Kharasch has no competing interests Dr. Clark has a consulting agreement with Teikoku Pharma USA (San Jose, California).

Figures

Figure 1.
Figure 1.
United States drug overdose deaths involving opioids 1999–2020 (November), by type of opioid. Data are accessed at https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm
See this image and copyright information in PMC

Comment in

  • Opioid-free Anesthesia: Comment.
    Chelly JE. Chelly JE. Anesthesiology. 2021 Oct 1;135(4):756-757. doi: 10.1097/ALN.0000000000003911. Anesthesiology. 2021. PMID: 34388818 No abstract available.
  • Opioid-free Anesthesia: Comment.
    Forget P, Mulier J, Lavand'homme P, De Baerdemaeker L, Pelosi P, de Boer HD. Forget P, et al. Anesthesiology. 2021 Oct 1;135(4):751-753. doi: 10.1097/ALN.0000000000003908. Anesthesiology. 2021. PMID: 34388823 No abstract available.
  • Opioid-free Anesthesia: Reply.
    Kharasch ED, Clark JD. Kharasch ED, et al. Anesthesiology. 2021 Oct 1;135(4):759-760. doi: 10.1097/ALN.0000000000003912. Anesthesiology. 2021. PMID: 34388824 Free PMC article. No abstract available.
  • Opioid-free Anesthesia: Comment.
    Ingrande J, Drummond JC. Ingrande J, et al. Anesthesiology. 2021 Oct 1;135(4):753-755. doi: 10.1097/ALN.0000000000003909. Anesthesiology. 2021. PMID: 34388825 No abstract available.

References

    1. Kharasch ED: Opioid half-lives and hemlines: The long and short of fashion. Anesthesiology 2015;122:969–70 - PMC - PubMed
    1. Society for Opioid Free Anesthesia.https://goopioidfree.com/, last accessed December 15, 2020
    1. Lirk P, Rathmell JP: Opioid-free anaesthesia: Con: it is too early to adopt opioid-free anaesthesia today. Eur J Anaesthesiol 2019;36:250–254 - PubMed
    1. Lavand’homme P: Opioid-free anaesthesia: Pro: damned if you don’t use opioids during surgery. Eur J Anaesthesiol 2019;36:247–249 - PubMed
    1. Wu CL, King AB, Geiger TM, Grant MC, Grocott MPW, Gupta R, Hah JM, Miller TE, Shaw AD, Gan TJ, Thacker JKM, Mythen MG, McEvoy MD: American Society for Enhanced Recovery and Perioperative Quality Initiative joint consensus statement on perioperative opioid minimization in opioid-naive patients. Anesth Analg 2019;129:567–577 - PMC - PubMed

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