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Review
. 2021 Oct;92(10):1042-1051.
doi: 10.1007/s00115-021-01079-z. Epub 2021 Feb 25.

[Deep brain stimulation in neurological and psychiatric diseases]

[Article in German]
Affiliations
Review

[Deep brain stimulation in neurological and psychiatric diseases]

[Article in German]
Stephan Klebe et al. Nervenarzt. 2021 Oct.

Abstract

Invasive deep brain stimulation (DBS) has become an established treatment procedure for a number of neurological diseases, especially movement disorders. The number of patients treated with DBS is continuously increasing, the technical development of DBS systems is progressing and new indications are currently being tested in studies. This review gives an overview of the current indications and an outlook on future developments of DBS in movement disorders and psychiatric diseases.

Die invasive Hirnstimulation (tiefe Hirnstimulation [THS], „deep brain stimulation“ [DBS]) ist mittlerweile ein etabliertes Therapieverfahren bei einer Reihe neurologischer Erkrankungen insbesondere Bewegungsstörungen. Die Anzahl der mit einer THS versorgten Patienten steigt stetig, die technische Entwicklung der THS-Systeme schreitet voran und neue Indikationen werden aktuell in Studien überprüft. Im folgenden Beitrag soll ein Überblick über die aktuellen Indikationen und ein Ausblick auf zukünftige Entwicklungen der THS bei Bewegungsstörungen und psychiatrischen Erkrankungen gegeben werden.

Keywords: Dystonia; Parkinsons Disease; Psychiatric diseases; Target selection; Tremor.

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References

    1. Svennilson E, Torvik A, Lowe R, Leksell L. Treatment of parkinsonism by stereotatic thermolesions in the pallidal region. A clinical evaluation of 81 cases. Acta Psychiatr Scand. 1960;35(3):358–377. doi: 10.1111/j.1600-0447.1960.tb07606.x. - DOI - PubMed
    1. Laitinen LV, Bergenheim AT, Hariz MI. Leksell’s posteroventral pallidotomy in the treatment of Parkinson’s disease. J Neurosurg. 1992;76(1):53–61. doi: 10.3171/jns.1992.76.1.0053. - DOI - PubMed
    1. Benabid AL, Pollak P, Gervason C, Hoffmann D, Gao DM, Hommel M, et al. Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet. 1991;337(8738):403–406. doi: 10.1016/0140-6736(91)91175-T. - DOI - PubMed
    1. Deep-Brain Stimulation for Parkinson’s Disease Study G. Obeso JA, Olanow CW, Rodriguez-Oroz MC, Krack P, Kumar R, et al. Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson’s disease. N Engl J Med. 2001;345(13):956–963. doi: 10.1056/NEJMoa000827. - DOI - PubMed
    1. Limousin P, Pollak P, Benazzouz A, Hoffmann D, Le Bas JF, Broussolle E, et al. Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. Lancet. 1995;345(8942):91–95. doi: 10.1016/S0140-6736(95)90062-4. - DOI - PubMed

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