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Review

Ethyl Loflazepate

No authors listed
In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
.
Free Books & Documents
Review

Ethyl Loflazepate

No authors listed.
Free Books & Documents

Excerpt

Ethyl loflazepate is not approved for marketing in the United States by the U.S. Food and Drug Administration. Available data indicate that the infant dose from milk might be rather high. An alternate drug with more published data and lower milk levels is preferred, especially while nursing a newborn or preterm infant. If ethyl loflazepate is used, monitor the infant for sedation, poor feeding and poor weight gain.

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References

    1. Nishimura A, Furugen A, Umazume T, et al. Benzodiazepine concentrations in the breast milk and plasma of nursing mothers: Estimation of relative infant dose. Breastfeed Med 2021;16:424-31. - PubMed
    1. Saito J, Tachibana Y, Wada YS, et al. Transfer of ethyl loflazepate into cord blood, breast milk, and infant's serum: A case report. J Clin Psychopharmacol 2022;42:416-8. - PubMed

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