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. 2021 Feb 26;70(8):278-279.
doi: 10.15585/mmwr.mm7008e1.

First Identified Cases of SARS-CoV-2 Variant B.1.1.7 in Minnesota - December 2020-January 2021

Melanie J Firestone, Alexandra J Lorentz, Xiong Wang, Kathryn Como-Sabetti, Sara Vetter, Kirk Smith, Stacy Holzbauer, Stephanie Meyer, Kristin Ehresmann, Richard Danila, Ruth Lynfield

First Identified Cases of SARS-CoV-2 Variant B.1.1.7 in Minnesota - December 2020-January 2021

Melanie J Firestone et al. MMWR Morb Mortal Wkly Rep. .

Abstract

On January 9, 2021, the Minnesota Department of Health (MDH) announced the identification of the SARS-CoV-2 variant of concern (VOC) B.1.1.7, also referred to as 20I/501Y.V1 and VOC 202012/01, in specimens from five persons; on January 25, MDH announced the identification of this variant in specimens from three additional persons. The B.1.1.7 variant, which is reported to be more transmissible than certain other SARS-CoV-2 lineages*,† (1), was first reported in the United Kingdom in December 2020 (1). As of February 14, 2021, a total of 1,173 COVID-19 cases of the B.1.1.7 variant had been identified in 39 U.S. states and the District of Columbia (2). Modeling data suggest that B.1.1.7 could become the predominant variant in the United States in March 2021 (3).

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Conflict of interest statement

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

Figures

FIGURE
FIGURE
Phylogenetic tree showing genetic distance between SARS-CoV-2–positive specimens with the B.1.1.7 variant (n = 8) and exposure histories related to travel, household contacts, and others in the community Abbreviation: SNV = single nucleotide variant. * Phylogenetic tree created using Interactive Tree of Life (version 5.7; European Molecular Biology Laboratory). https://itol.embl.de/ † MN-MDH-2253 and MN-MDH-2255 were identical, and MN-MDH-2252 was within one SNV. MN-MDH-2252 and MN-MDH-2253 were collected from persons who were household contacts. Two specimens from international travelers, MN-MDH-2254 and MN-CDC-STM-0000013, did not have sequences similar to those identified in Minnesota. § International and domestic travel occurred during the 14 days before illness onset or specimen collection, including onset of illness in persons who received positive SARS-CoV-2 test results while away from Minnesota. MN-CDC-STM-153, MN-MDH-2416, and MN-MDH-2415 were clustered together within one to three SNVs. These three specimens were from persons who reported travel to California in the 14 days before illness onset or specimen collection, including one who received a positive test result while in California and isolated there before returning to Minnesota.
See this image and copyright information in PMC

References

    1. Public Health England. Investigation of novel SARS-COV-2 variant: variant of concern 202012/01. London, United Kingdom: Public Health England; 2020. https://assets.publishing.service.gov.uk/government/uploads/system/uploa...
    1. CDC. U.S. COVID-19 cases caused by variants. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. https://www.cdc.gov/coronavirus/2019-ncov/transmission/variant-cases.html
    1. Galloway SE, Paul P, MacCannell DR, et al. Emergence of SARS-CoV-2 B.1.1.7 lineage—United States, December 29, 2020–January 12, 2021. MMWR Morb Mortal Wkly Rep 2021;70:95–9. 10.15585/mmwr.mm7003e2 - DOI - PMC - PubMed