Recent progress in preparation and applications of chitosan/calcium phosphate composite materials

Abstract

Studying the development of unique materials from sustainable and renewable resources has gained increasing concern due to the depletion of fossil resources. Chitosan and its derivatives have been considered as versatile candidates for preparing attractive materials. The fabrication of chitosan/calcium phosphate composite compounds has received much attention for the development of numerous promising products in different fields. In this short review, recent preparation strategies for chitosan/calcium phosphate composites such as freeze casting, vacuum-assisted filtration, and biomimetic mineralization were discussed. The review presented their advances for diverse applications such as bone tissue engineering implants, drug delivery, wound healing, dental caries, as well adsorption of organic and heavy metals from polluted water. The challenges and future perspectives for the application of chitosan/calcium phosphate materials in biomedical and environmental applications were also involved in this review article.

Keywords: Biomineralization; Calcium phosphate; Chitosan; Composites.