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Review
. 2021 Apr;39(4):327-329.
doi: 10.1016/j.tibtech.2021.02.005. Epub 2021 Feb 23.

Reductive Glycine Pathway: A Versatile Route for One-Carbon Biotech

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Review

Reductive Glycine Pathway: A Versatile Route for One-Carbon Biotech

Nico J Claassens. Trends Biotechnol. 2021 Apr.

Abstract

Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimilating rGlyP. Its engineering in diverse hosts could help the transformation toward renewable, one-carbon-based bioproduction.

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Conflict of interest statement

Declaration of Interests None declared by author.

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