Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jan;71(1):5-6.
doi: 10.1136/gutjnl-2020-323973. Epub 2021 Feb 25.

Acute-on-chronic liver failure: a global disease

Martin Schulz  1 , Jonel Trebicka  2   3
Affiliations
Comment

Acute-on-chronic liver failure: a global disease

Martin Schulz et al. Gut. 2022 Jan.
No abstract available

Keywords: cirrhosis; liver failure.

PubMed Disclaimer

Conflict of interest statement

Competing interests: JT has received speaking and/or consulting fees from Gore, Bayer, Alexion, MSD, Gilead, Intercept, Norgine, Grifols, Versantis and Martin Pharmaceutical.

Figures

Figure 1
Figure 1
The figure depicts the known world-wide prevalence (A) and 90-day mortality (B) of acute-on-chronic liver failure (ACLF) reviewed in the meta-analysis Mezzano et al.
See this image and copyright information in PMC

Comment on

References

    1. Arroyo V, Moreau R, Jalan R. Acute-On-Chronic liver failure. N Engl J Med 2020;382:2137–45. 10.1056/NEJMra1914900 - DOI - PubMed
    1. Mezzano G, Juanola A, Cardenas A. Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis. Gut 2022;71:148–55. 10.1136/gutjnl-2020-322161 - DOI - PubMed
    1. Mezzano G, Juanola A, Cardenas A. Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis. Gut 2022;71:148–55. 10.1136/gutjnl-2020-322161 - DOI - PubMed
    1. Trebicka J, Fernandez J, Papp M, et al. The predict study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology. J Hepatol 2020;73:842–54. 10.1016/j.jhep.2020.06.013 - DOI - PubMed
    1. Trebicka J, Fernandez J, Papp M, et al. Predict identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis. J Hepatol 2020. 10.1016/j.jhep.2020.11.019. [Epub ahead of print: 20 Nov 2020]. - DOI - PubMed

MeSH terms