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Meta-Analysis
. 2021 Feb 25;11(1):4592.
doi: 10.1038/s41598-021-84259-w.

Changing gloves during cesarean section for prevention of postoperative infections: a systematic review and meta-analysis

Siwanon Rattanakanokchai  1 , Nuntasiri Eamudomkarn  2 , Nampet Jampathong  2 , Bao-Yen Luong-Thanh  3 , Chumnan Kietpeerakool  4
Affiliations
Meta-Analysis

Changing gloves during cesarean section for prevention of postoperative infections: a systematic review and meta-analysis

Siwanon Rattanakanokchai et al. Sci Rep. .

Erratum in

Abstract

This systematic review and meta-analysis was conducted to assess associations between changing gloves during cesarean section (CS) and postoperative infection. A literature search was conducted using the major electronic databases MEDLINE, Scopus, ISI Web of Science, PubMed, CINAHL, and CENTRAL from their inception to September 2020. Randomized controlled trials (RCTs) comparing glove change during CS to no glove change were included. Outcomes of interest were endometritis, febrile morbidity, and incisional surgical site infection (SSI). GRADE approach was applied to assess the quality of evidence. Ten reports of six studies involving 1707 participants were included in the analyses. Glove change was associated with a reduction in the risk of incisional SSI following CS (pooled RR 0.49, 95% CI 0.30, 0.78; moderate quality of evidence). Compared to no glove change, glove change during CS did not reduce the risks of endometritis (pooled RR 1.00, 95% CI 0.80, 1.24; low quality of evidence) or febrile morbidity (pooled RR 0.85, 95% CI 0.43, 1.71; very low quality of evidence). Changing gloves during CS was associated with a decreased risk of incisional SSI. The risks of postoperative endometritis and febrile morbidity were not altered by changing gloves.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
PRISMA diagram.
Figure 2
Figure 2
Summary risk of bias of included studies.
Figure 3
Figure 3
Effects of intervention on (A) Endometritis, (B) Febrile morbidity, and (C) Incisional surgical site infection. (n) = not specified placental delivery method, (m) = manual placental removal, (s) = spontaneous placental removal, * heterogeneity of two-level meta-analysis explained by I2, †heterogeneity of three-level meta-analysis explained by variance within the study (σ22), ‡heterogeneity of three-level meta-analysis explained by variance between the studies (σ32)
Figure 4
Figure 4
Subgroup analyses of the effects of intervention by placental delivery method and timing of glove change. Manual = manual placental removal, Spontaneous = spontaneous placental delivery, * heterogeneity of two-level meta-analysis explained by I2, †heterogeneity of three-level meta-analysis explained by variance within the study (σ22), ‡heterogeneity of three-level meta-analysis explained by variance between the studies (σ32)
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References

    1. Ye J, et al. Association between rates of caesarean section and maternal and neonatal mortality in the 21st century. Obstet. Anesth. Dig. 2017;37:17–18. doi: 10.1097/01.aoa.0000512009.11462.7d. - DOI - PMC - PubMed
    1. Zuarez-Easton S, Zafran N, Garmi G, Salim R. Postcesarean wound infection: Prevalence, impact, prevention, and management challenges. Int. J. Womens. Health. 2017;9:81–88. doi: 10.2147/IJWH.S98876. - DOI - PMC - PubMed
    1. Cedergren MI. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet. Gynecol. Surv. 2004;59:489–491. doi: 10.1097/00006254-200407000-00002. - DOI - PubMed
    1. Kankoon N, et al. Cesarean rates and severe maternal and neonatal outcomes according to the Robson 10-Group Classification System in Khon Kaen Province, Thailand. Int. J. Gynecol. Obstet. 2018;140:191–197. doi: 10.1002/ijgo.12372. - DOI - PubMed
    1. Kietpeerakool C, et al. Pregnancy outcomes of women with previous caesarean sections: Secondary analysis of World Health Organization Multicountry Survey on Maternal and Newborn Health. Sci. Rep. 2019;9:1–9. doi: 10.1038/s41598-019-46153-4. - DOI - PMC - PubMed