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. 2021 Jun;56(6):1690-1693.
doi: 10.1002/ppul.25338. Epub 2021 Mar 13.

Successful intravascular pulmonary lithotripsy in a child with chronic thromboembolic pulmonary hypertension

Affiliations

Successful intravascular pulmonary lithotripsy in a child with chronic thromboembolic pulmonary hypertension

Sabine Diepenbruck et al. Pediatr Pulmonol. 2021 Jun.

Abstract

Intravascular lithotripsy (IVL) is a novel method based on pulsatile ultrasonic pressure waves specifically aimed to modify circumferential and transmural calcium plaques. We report on the successful application of a shockwave IVL catheter® in a child with chronic thromboembolic pulmonary hypertension due to calcified thrombi in both lower lobes. Compared to conventional high-pressure balloon angioplasty, a significant perfusion-improvement was achieved with a shockwave IVL catheter® (4 mm) of the treated right pulmonary artery branch. Furthermore, subsequent surgical thrombectomy was reported to be considerably easier for the shockwave-treated thrombotic areas than the high-pressure balloon-only-treated thrombus. In conclusion, the shockwave IVL catheter® may be a promising option in chronic thromboembolic lesions in PA (pulmonary artery) position, and furthermore might be an option when treating children.

Keywords: chronic thrombembolic pulmonary hypertension; infant; pulmonary intravascular lithotripsy.

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References

REFERENCES

    1. Lingeman JE, McAteer JA, Gnessin E, Evan AP. Shock wave lithotripsy: advances in technology and technique. Nat Rev Urol. 2009;6(12):660-670. https://doi.org/10.1038/nrurol.2009.216
    1. Brinton TJ, Ali ZA, Hill JM, et al. Feasibility of shockwave coronary intravascular lithotripsy for the treatment of calcified coronary stenoses. Circulation. 2019;139(6):834-836. https://doi.org/10.1161/CIRCULATIONAHA.118.036531
    1. Ali ZA, Nef H, Escaned J, et al. Safety and effectiveness of coronary intravascular lithotripsy for treatment of severely calcified coronary stenoses: the Disrupt CAD II Study. Circ Cardiovasc Interv. 2019;12(10):e008434. https://doi.org/10.1161/CIRCINTERVENTIONS.119.008434
    1. Adams G, Shammas N, Mangalmurti S, et al. Intravascular lithotripsy for treatment of calcified lower extremity arterial stenosis: initial analysis of the Disrupt PAD III Study. J Endovasc Ther. 2020;27(3):473-480. https://doi.org/10.1177/1526602820914598
    1. Kereiakes DJ, Hill JM, Ben-Yehuda O, Maehara A, Alexander B, Stone GW. Evaluation of safety and efficacy of coronary intravascular lithotripsy for treatment of severely calcified coronary stenoses: Design and rationale for the Disrupt CAD III trial. Am Heart J. 2020;225:10-18. https://doi.org/10.1016/j.ahj.2020.04.005