Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Dec:25:1.
doi: 10.7812/TPP/20.140.

COVID-19 Pandemic and the Burden of Acute Kidney Injury: The Known and the Unknown

Talha H Imam  1
Affiliations
Comment

COVID-19 Pandemic and the Burden of Acute Kidney Injury: The Known and the Unknown

Talha H Imam. Perm J. 2020 Dec.

Abstract

The present pandemic of severe acute respiratory syndrome is caused by the coronavirus (2019-nCoV), commonly called COVID-19. Starting from China, it has spread worldwide, causing major morbidity and mortality. It primarily involves the pulmonary system, but other organ systems are not spared. Treatment is still elusive and evolving. The exact pathogenesis of renal damage from COVID-19 virus and the magnitude of renal failure in this infection are not very clear. PubMed was searched to identify published literature from 2019 to present using the following keywords: COVID-19, acute kidney injury, creatinine, blood urea nitrogen, chronic kidney disease, renal replacement therapy, and dialysis. Cited references were also used to further identify relevant articles and literature elsewhere on the web. This review looks at the burden and influence of the COVID-19 pandemic on the kidneys and on the implications it will have on public health planning.

PubMed Disclaimer

Conflict of interest statement

Disclosure Statement: The author(s) have no conflicts of interest to disclose.

Comment on

  • Clinical Characteristics of Coronavirus Disease 2019 in China.
    Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Zhong NS; China Medical Treatment Expert Group for Covid-19. Guan WJ, et al. N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi: 10.1056/NEJMoa2002032. Epub 2020 Feb 28. N Engl J Med. 2020. PMID: 32109013 Free PMC article.

References

    1. Li Q, Guan X, Wu P, et al. . Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 2020 Mar;382(13):1199-207. DOI: 10.1056/nejmoa2001316 - DOI - PMC - PubMed
    1. Guan W, Ni Z, Hu Y, et al. . Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020 Apr. 382(18):1708-20. DOI: 10.1056/NEJMoa2002032 - DOI - PMC - PubMed
    1. Wang D, Hu B, Hu C, et al. . Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. J Am Med Assoc 2020 Mar;323(11):1061-9. DOI: 10.1001/jama.2020.1585, PMID:32031570 - DOI - PMC - PubMed
    1. WHO Coronavirus disease 2019 (Covid-19) situation report. Accessed April 15, 2020. https://www.who.int/docs/default-source/coronaviruse/situation-reports/2....
    1. Omer SB, Malani P, Rio CD. The COVID-19 pandemic in the US: A clinical update. J Am Med Assoc 2020 May;323(18):1767-8. DOI: 10.1001/jama.2020.5788 - DOI - PubMed