Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 May;28(4):1123-1130.
doi: 10.1111/odi.13825. Epub 2021 Mar 5.

A novel lightweight deep convolutional neural network for early detection of oral cancer

Affiliations

A novel lightweight deep convolutional neural network for early detection of oral cancer

Fahed Jubair et al. Oral Dis. 2022 May.

Abstract

Objectives: To develop a lightweight deep convolutional neural network (CNN) for binary classification of oral lesions into benign and malignant or potentially malignant using standard real-time clinical images.

Methods: A small deep CNN, that uses a pretrained EfficientNet-B0 as a lightweight transfer learning model, was proposed. A data set of 716 clinical images was used to train and test the proposed model. Accuracy, specificity, sensitivity, receiver operating characteristics (ROC) and area under curve (AUC) were used to evaluate performance. Bootstrapping with 120 repetitions was used to calculate arithmetic means and 95% confidence intervals (CIs).

Results: The proposed CNN model achieved an accuracy of 85.0% (95% CI: 81.0%-90.0%), a specificity of 84.5% (95% CI: 78.9%-91.5%), a sensitivity of 86.7% (95% CI: 80.4%-93.3%) and an AUC of 0.928 (95% CI: 0.88-0.96).

Conclusions: Deep CNNs can be an effective method to build low-budget embedded vision devices with limited computation power and memory capacity for diagnosis of oral cancer. Artificial intelligence (AI) can improve the quality and reach of oral cancer screening and early detection.

Keywords: artificial intelligence; computer-aided diagnosis; convolutional neural network; deep learning; early detection; oral cancer; tongue cancer.

PubMed Disclaimer

References

REFERENCES

    1. AAOM Clinical Practice Statement (2016). Subject: Oral cancer examination and screening. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 122(2), 174-175.
    1. Attardo, S., Chandrasekar, V. T., Spadaccini, M., Maselli, R., Patel, H. K., Desai, M., Capogreco, A., Badalamenti, M., Galtieri, P. A., Pellegatta, G., Fugazza, A., Carrara, S., Anderloni, A., Occhipinti, P., Hassan, C., Sharma, P., & Repici, A. (2020). Artificial intelligence technologies for the detection of colorectal lesions: The future is now. World Journal of Gastroenterology, 26(37), 5606-5616. https://doi.org/10.3748/wjg.v26.i37.5606
    1. Aubreville, M., Knipfer, C., Oetter, N., Jaremenko, C., Rodner, E., Denzler, J., Bohr, C., Neumann, H., Stelzle, F., & Maier, A. (2017). Automatic classification of cancerous tissue in laserendomicroscopy images of the oral cavity using deep learning. Scientific Reports, 7, 11979.
    1. Buda, M., Maki, A., & Mazurowski, M. A. (2018). A systematic study of the class imbalance problem in convolutional neural networks. Neural Networks, 106, 249-259.
    1. Califano, J., Van der Riet, P., Westra, W., Hawroz, H., Clayman, G., Piantadosi, S., Corio, R., Lee, D., Greenberg, B., Koch, W., & Sidransky, D. (1996). Genetic progression model for head and neck cancer: Implications for head and neck cancer: Implications for field cancerization. Cancer Research, 56, 2488-2492.

LinkOut - more resources