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Review
. 2021 Feb 26;31(1):10.
doi: 10.1038/s41533-021-00223-1.

Are smokers protected against SARS-CoV-2 infection (COVID-19)? The origins of the myth

Affiliations
Review

Are smokers protected against SARS-CoV-2 infection (COVID-19)? The origins of the myth

Naomi A van Westen-Lagerweij et al. NPJ Prim Care Respir Med. .

Abstract

A number of recent studies have found low percentages of smokers among COVID-19 patients, causing scientists to conclude that smokers may be protected against SARS-CoV-2 infection. National and international media were interested in this story and we soon began receiving questions about this topic in general practice. In this article, we shed light on the process that resulted in the misinterpretation of observational research by scientists and the media. We also point out the methodological flaws of various studies on which hasty conclusions were based. Finally, we address the role of primary healthcare providers in mitigating the consequences of erroneous claims about a protective effect of smoking.

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Conflict of interest statement

The authors declare no competing interests.

References

    1. Arcavi L, Benowitz NL. Cigarette smoking and infection. Arch. Intern. Med. 2004;164:2206–2216. doi: 10.1001/archinte.164.20.2206. - DOI - PubMed
    1. Alraddadi BM, et al. Risk factors for primary Middle East respiratory syndrome coronavirus illness in humans, Saudi Arabia, 2014. Emerg. Infect. Dis. 2016;22:49–55. doi: 10.3201/eid2201.151340. - DOI - PMC - PubMed
    1. Simons, D., Shahab, L., Brown, J. & Perski, O. The association of smoking status with SARS‐CoV‐2 infection, hospitalization and mortality from COVID‐19: a living rapid evidence review with Bayesian meta‐analyses (version 7). Addiction (2020). - PMC - PubMed
    1. Kodvanj, I., Homolak, J., Virag, D. & Trkulja V. Publishing of COVID-19 preprints in peer-reviewed journals, preprinting trends, public discussion and quality issues. Preprint at bioRxiv.https://www.biorxiv.org/content/10.1101/2020.11.23.394577v3 (2020). - DOI - PMC - PubMed
    1. Lachapelle, F. COVID-19 preprints and their publishing rate: an improved method. Preprint at MedRxivhttps://www.medrxiv.org/content/10.1101/2020.09.04.20188771v4 (2020). - DOI