Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Feb 26;11(1):4812.
doi: 10.1038/s41598-021-84262-1.

Molecular characteristics of Neisseria meningitidis in Qatar

Manal Mahmoud Hamed #  1 , Fayaz Ahmad Mir #  2 , Emad Bashier Ibrahim Elmagboul  2 , Abdullatif Al-Khal  2 , Muna A Rahman S Al Maslamani  2 , Anand Sarwottam Deshmukh  2 , Hamad Eid Al-Romaihi  3 , Mohd Ahmed M Sharif Janahi  2 , Fatma Ben Abid  2 , Adila Shaukat Ali Kashaf  2 , Gulab Sher  2 , Vinod Kumar Gupta  2 , Godwin J Wilson  2 , Junais Kadalayi  2 , Sanjay H Doiphode  2
Affiliations

Molecular characteristics of Neisseria meningitidis in Qatar

Manal Mahmoud Hamed et al. Sci Rep. .

Abstract

The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to 2018 were revived and identified by Vitek, and susceptibility on the basis of the E test was retrieved from the patient's files. The revived isolates were subjected to multilocus sequence typing. The most common serogroup (19) of N. meningitidis was W135, of which 12 were isolated from blood and CSF. ST-11 was the most predominant ST clonal complex causing N. meningitidis cases (61.53%). Clonal complex ST-41/44 was the second most observed complex (3, 2 of which were related to serogroup B). The most frequent sequence type was 9596 (8 isolates). Determining the molecular pattern of N. meningitidis in Qatar is helpful for understanding the strains circulating in Qatar, and the study of the resistance trend of such strains may be very helpful for empirical treatment of future patients.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Nationality distribution among the patients.
Figure 2
Figure 2
Age distribution among patients.
Figure 3
Figure 3
Serogroup distribution among all isolates.
Figure 4
Figure 4
Occurrence of Neisseria meningitidis serotypes.
See this image and copyright information in PMC

References

    1. Oppenheim BA. Antibiotic resistance in Neisseria meningitidis. Clin. Infect. Dis. 1997;24(Suppl 1):S98–101. doi: 10.1093/clinids/24.supplement_1.s98. - DOI - PubMed
    1. Romero-Gomez MP, Rentero Z, Pano JR, Mingorance J. Bacteraemic pneumonia caused by Neisseria meningitidis serogroup Y. Respir. Med. Case Rep. 2012;5:23–24. doi: 10.1016/j.rmedc.2011.11.005. - DOI - PMC - PubMed
    1. Harrison LH. Epidemiological profile of meningococcal disease in the United States. Clin. Infect. Dis. 2010;50(Suppl 2):S37–44. doi: 10.1086/648963. - DOI - PMC - PubMed
    1. (NCIRD), N. C. f. I. a. R. D. Meningeococcal disease. https://www.cdc.gov/meningococcal/index.html.
    1. Ceyhan M, et al. Meningococcal disease in the Middle East and North Africa: an important public health consideration that requires further attention. Int. J. Infect Dis. IJID. 2012;16:e574–582. doi: 10.1016/j.ijid.2012.03.011. - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources