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Review
. 2021 Jan;68(1):92-98.
doi: 10.1016/j.ijtb.2020.09.021. Epub 2020 Sep 28.

A review: Epidemiology, pathogenesis and prospect in developing vaccines for novel Coronavirus (COVID-19)

Pratibha Gupta  1
Affiliations
Review

A review: Epidemiology, pathogenesis and prospect in developing vaccines for novel Coronavirus (COVID-19)

Pratibha Gupta. Indian J Tuberc. 2021 Jan.

Abstract

In December 2019, a large number of coronavirus cases were emerged in Wuhan, Hubei Province, China and rapidly spread to different countries and territories around the world within four months. The World Health Organization (WHO) declared this outbreak as a global health emergency. The spread of COVID-19 over globe is highly contagious; they transmitted from person-to-person through small droplets of infected person. Many diagnosis and treatment methods have been implemented to reduce and control the outbreak. Efforts have been made to develop coronavirus vaccine against S protein or spike glycoprotein of coronavirus. COVID-19 outbreak will affect the Gross Domestic Product (GDP) of the world. At the time of preparing manuscript, total number of active cases reaches to more than 8.9 million and confirmed death reaches to approx. 4.6 lakh. This article highlights the ongoing research and advances in designing vaccine and therapeutics against COVID-19 and also focusing on the epidemiology, transmission, future direction and control the spread of infectious diseases.

Keywords: COVID-19; Convalescent plasma transfusion; Economic effect; Epidemiology; Vaccines.

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Conflict of interest statement

Conflicts of interest The author has none to declare.

Figures

Fig. 1
Fig. 1
Skeleton of coronavirus; inside and outside morphology.
Fig. 2
Fig. 2
Map of spread COVID-19 global outbreak as on June 28, 2020. Blue colour indicates decrease in coronavirus cases where as orange and red colour indicates the increasing number of coronavirus cases.
Fig. 3
Fig. 3
Impact of COVID-19 on GDP growth rate; according to World Economic Growth Projection.
See this image and copyright information in PMC

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