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. 2021 Mar;37(2):175-182.
doi: 10.1007/s12055-020-00925-0. Epub 2020 Mar 25.

Mitral valve repair in children with rheumatic heart disease

Affiliations

Mitral valve repair in children with rheumatic heart disease

Srirup Chatterjee et al. Indian J Thorac Cardiovasc Surg. 2021 Mar.

Abstract

Purpose: Rheumatic heart disease is the most common acquired heart disease in children in developing countries. The heart valve lesions produce severe hemodynamic changes due to scarring of the valves over time. Around 15.6 million people are affected by rheumatic heart disease (RHD), and 230,000 die around the globe annually. Valve repair should be the primary goal, although it is technically challenging because of the fact that rheumatic process evolves making repair outcomes variable.

Methods: We reviewed the literature for the various techniques done for mitral valve repair in children with rheumatic heart disease. Early and late results of repair were compared with the results found for mitral valve repair done for such children.

Results: Prosthetic heart valve implantation in children has major negative impact on their immediate- and long-term survival as well as on quality of their life. Valve repair is associated with improved ventricular function because the normal valve tissue and subvalvular apparatus are preserved, reduced complications related to prosthetic valve, and lower in-hospital and late mortality.

Conclusion: In children, the results of mitral valve replacement were found to be inferior to those of mitral valve repair. The reoperation rates are similar in patients undergoing initial repair or replacement, which favors repair as an option. In developing world, rheumatic mitral valve disease is more prevalent where adequate facilities for monitoring of prosthetic valve function and management of anticoagulation therapy are not easily available. Valve repair therefore should be the primary goal.

Keywords: Annuloplasty; Artificial chordae; Mitral valve repair; Pericardial patch augmentation; Rheumatic heart disease.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Measuring the anterior leaflet
Fig. 2
Fig. 2
Annuloplasty ring
Fig. 3
Fig. 3
Chordal transfer
Fig. 4
Fig. 4
Commisurotomy
Fig. 5
Fig. 5
Pericardial patch augmentation
Fig. 6
Fig. 6
Chordal shortening
Fig. 7
Fig. 7
Thickened papillary muscle
Fig. 8
Fig. 8
Leaflet peeling/shaving

References

    1. Mendis S, Puska P, Norrving B, World Health Organization. Global atlas on cardiovascular disease prevention and control. Geneva: World Health Organization; 2011.
    1. Yakub MA, Dillon J, Krishna Moorthy PS, Pau KK, Nordin MN. Is rheumatic aetiology a predictor of poor outcome in the current era of mitral valve repair? Contemporary long-term results of mitral valve repair in rheumatic heart disease. Eur J Cardiothorac Surg. 2013;44:673–681. doi: 10.1093/ejcts/ezt093. - DOI - PubMed
    1. Dillon J, Yakub MA, Kong PK, Ramli MF, Jaffar N, Gaffar IF. Comparative long-term results of mitral valve repair in adults with chronic rheumatic disease and degenerative disease: is repair for “burnt-out” rheumatic disease still inferior to repair for degenerative disease in the current era? J Thorac Cardiovasc Surg. 2015;149:771–779. doi: 10.1016/j.jtcvs.2014.08.066. - DOI - PubMed
    1. David TE, Burns RJ, Bacchus CM, Druck MN. Mitral valve replacement for mitral regurgitation with and without preservation of chordae tendineae. J Thorac Cardiovasc Surg. 1984;88:718–725. doi: 10.1016/S0022-5223(19)35439-X. - DOI - PubMed
    1. Goldman ME, Mora F, Guarino T, Fuster V, Mindich BP. Mitral valvuloplasty is superior to valve replacement for preservation of left ventricular function: an intraoperative two-dimensional echocardiography study. J Am Coll Cardiol. 1987;10:568–575. doi: 10.1016/S0735-1097(87)80199-7. - DOI - PubMed

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