Cutaneous Metastasis vs. Isolated Skin Recurrence of Invasive Breast Carcinoma after Modified Radical Mastectomy
- PMID: 33643670
- PMCID: PMC7902130
- DOI: 10.1155/2021/6673289
Cutaneous Metastasis vs. Isolated Skin Recurrence of Invasive Breast Carcinoma after Modified Radical Mastectomy
Abstract
Background: Five to ten percent of the patients with operable breast cancer develop a chest wall recurrence within 10 years following the mastectomy. One of the most distressing presentations of locally recurrent breast cancer is the appearance of cutaneous metastases. To the best of authors' knowledge, there is no study distinguishing skin metastasis from local recurrence, so the main aim of this report was to elucidate if these two features are important in the prognosis and management of the disease. Case Presentation. A 51-year-old woman referred to the breast clinic due to a painful mass in the left breast. The patient underwent the modified radical mastectomy (MRM) and left axillary lymph node dissection followed by 30 sessions of radiotherapy and 8 sessions of chemotherapy (T3N1M0, ER-, and HER2+). About 15 months after the surgery, she presented with redness and eruptive lesions over the mastectomy scar that increased in size within a three-month follow-up.
Conclusion: Mastectomy is not an absolute cure in the treatment of an invasive breast cancer because almost always, there is a recurrence risk and possibility of metastasis. It is vital to differentiate between local recurrence and skin metastasis because it would alter the overall treatment decision, prognosis, and patient outcomes.
Copyright © 2021 Reza Hosseinpour and Mohammad Javad Yavari Barhaghtalab.
Conflict of interest statement
The authors of this article declare no conflicts of interest.
Figures
Similar articles
-
Cutaneous Metastasis in Breast Cancer: A Case Series.Cureus. 2023 Jun 8;15(6):e40109. doi: 10.7759/cureus.40109. eCollection 2023 Jun. Cureus. 2023. PMID: 37425494 Free PMC article.
-
Locoregional recurrence of breast cancer following mastectomy: always a fatal event? Results of univariate and multivariate analysis.Int J Radiat Oncol Biol Phys. 1997 Mar 1;37(4):853-63. doi: 10.1016/s0360-3016(96)00556-1. Int J Radiat Oncol Biol Phys. 1997. PMID: 9128962
-
[A Case of Recurrent Breast Cancer with Contralateral Axillary Node Recurrence Cured after Mastectomy for Ipsilateral Breast Tumor Recurrence].Gan To Kagaku Ryoho. 2019 Dec;46(13):2018-2020. Gan To Kagaku Ryoho. 2019. PMID: 32157045 Japanese.
-
Management of operable breast cancer: the surgeon's view.Cancer. 1978 Oct;42(4):2066-77. doi: 10.1002/1097-0142(197810)42:4<2066::aid-cncr2820420458>3.0.co;2-v. Cancer. 1978. PMID: 101302 Review.
-
Low risk of locoregional recurrence of primary breast carcinoma after treatment with a modification of the Halsted radical mastectomy and selective use of radiotherapy.Cancer. 1999 Apr 15;85(8):1773-81. Cancer. 1999. PMID: 10223572 Review.
Cited by
-
Cutaneous Metastasis of Triple Negative Breast Cancer: A Case Report and Review of Literature.Cureus. 2025 Mar 2;17(3):e79926. doi: 10.7759/cureus.79926. eCollection 2025 Mar. Cureus. 2025. PMID: 40171370 Free PMC article.
-
Evaluation of the quality and accuracy of breast cancer knowledge among persian language websites.BMC Health Serv Res. 2022 Dec 20;22(1):1560. doi: 10.1186/s12913-022-08966-4. BMC Health Serv Res. 2022. PMID: 36539766 Free PMC article. Review.
-
Cutaneous metastases as a primary manifestation of invasive ductal carcinoma of the breast: a case report.Ann Med Surg (Lond). 2023 May 10;85(6):3062-3065. doi: 10.1097/MS9.0000000000000835. eCollection 2023 Jun. Ann Med Surg (Lond). 2023. PMID: 37363526 Free PMC article.
References
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous