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Editorial
. 2021 Mar 1;106(3):661-663.
doi: 10.3324/haematol.2020.270496.

Recognition of thrombotic risk of thrombocytosis in iron deficiency

Hanny Al-Samkari  1 , Craig M Kessler  2 , Michael Auerbach  2
Affiliations
Editorial

Recognition of thrombotic risk of thrombocytosis in iron deficiency

Hanny Al-Samkari et al. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Rates of thrombocytosis and thrombosis among patients with iron-deficiency anemia. Rates of thrombocytosis and thrombosis in a recent large clinical database study of over six million patients, supported by extensive chart review to exclude alternative confounding causes of thrombocytosis and confirm thrombotic events.
See this image and copyright information in PMC

Comment on

References

    1. Loo M, Beguin Y. The effect of recombinant human erythropoietin on platelet counts is strongly modulated by the adequacy of iron supply. Blood. 1999;93(10):3286-3293. - PubMed
    1. Henry DH, Dahl NV, Auerbach MA. Thrombocytosis and venous thromboembolism in cancer patients with chemotherapy induced anemia may be related to ESA induced iron restricted erythropoiesis and reversed by administration of IV iron. Am J Hematol. 2012;87(3):308-310. - PubMed
    1. Henry DH, Dahl NV, Auerbach M, Tchekmedyian S, Laufman LR. Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. Oncologist. 2007;12(2):231-242. - PubMed
    1. Song AB, Kuter DJ, Al-Samkari H. Characterization of the rate, predictors, and thrombotic complications of thrombocytosis in iron deficiency anemia. Am J Hematol. 2020. Jul 3. doi: 10.1002/ajh.25925. [Epub ahead of print]. - PubMed
    1. Jimenez K, Leitner F, Leitner A, et al. . Iron deficiency-induced thrombocytosis increases thrombotic tendency in rats. Haematologica. 2020;106(3):783-795. - PMC - PubMed

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