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. 2021:2278:71-85.
doi: 10.1007/978-1-0716-1274-3_7.

Phageome Analysis of Bifidobacteria-Rich Samples

Brian McDonnell  1 , Eoghan Casey  1 , Christian Milani  2   3 , Gabriele Andrea Lugli  2 , Alice Viappiani  3 , Jennifer Mahony  1 , Marco Ventura  2 , Douwe van Sinderen  4
Affiliations

Phageome Analysis of Bifidobacteria-Rich Samples

Brian McDonnell et al. Methods Mol Biol. 2021.

Abstract

Bifidobacteria are important early colonizers of the human intestinal tract. The relative abundance of bifidobacterial species may be modulated, in part, by bacteriophage activity. Metagenomic studies of these populations is a crucial step in understanding this important interaction. This chapter outlines the technical instructions required to analyze the virome of a bifidobacteria-rich sample, for example, an infant fecal sample.

Keywords: DNA; Fecal; Metagenome; Phage; Sequencing.

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