Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 May;64(5):523-524.
doi: 10.1165/rcmb.2021-0083ED.

Can Eosinophils Prevent Lung Injury? Ask PHIL

Christopher M Evans  1 , Alexandra L McCubbrey  1   2
Affiliations
Editorial

Can Eosinophils Prevent Lung Injury? Ask PHIL

Christopher M Evans et al. Am J Respir Cell Mol Biol. 2021 May.
No abstract available

PubMed Disclaimer

Comment on

  • IL-33-mediated Eosinophilia Protects against Acute Lung Injury.
    Krishack PA, Hollinger MK, Kuzel TG, Decker TS, Louviere TJ, Hrusch CL, Sperling AI, Verhoef PA. Krishack PA, et al. Am J Respir Cell Mol Biol. 2021 May;64(5):569-578. doi: 10.1165/rcmb.2020-0166OC. Am J Respir Cell Mol Biol. 2021. PMID: 33571420 Free PMC article.

References

    1. Krishack PA, Hollinger MK, Kuzel TG, Decker TS, Louviere TJ, Hrusch CL, et al. IL-33–mediated eosinophilia protects against acute lung injury. Am J Respir Cell Mol Biol. 2021;64:569–578. - PMC - PubMed
    1. Dulek DE, Newcomb DC, Goleniewska K, Cephus J, Zhou W, Reiss S, et al. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infect Immun. 2014;82:3723–3739. - PMC - PubMed
    1. Sanfilippo AM, Furuya Y, Roberts S, Salmon SL, Metzger DW. Allergic lung inflammation reduces tissue invasion and enhances survival from pulmonary pneumococcal infection in mice, which correlates with increased expression of transforming growth factor β1 and SiglecF(low) alveolar macrophages. Infect Immun. 2015;83:2976–2983. - PMC - PubMed
    1. Adamko DJ, Yost BL, Gleich GJ, Fryer AD, Jacoby DB. Ovalbumin sensitization changes the inflammatory response to subsequent parainfluenza infection: eosinophils mediate airway hyperresponsiveness, m(2) muscarinic receptor dysfunction, and antiviral effects. J Exp Med. 1999;190:1465–1478. - PMC - PubMed
    1. Clement CG, Tuvim MJ, Evans CM, Tuvin DM, Dickey BF, Evans SE. Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice. Respir Res. 2009;10:70. - PMC - PubMed

Publication types

LinkOut - more resources