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Comment
. 2021 Mar 2;19(1):93.
doi: 10.1186/s12967-021-02762-0.

Could asymptomatic carriers spread the SARS-CoV-2 infection? Experience from the Italian second wave

Luigi Atripaldi  1 , Silvia Sale  1 , Mariaelena Capone  2 , Vincenzo Montesarchio  3 , Roberto Parrella  4 , Gerardo Botti  5 , Paolo Antonio Ascierto  6 , Gabriele Madonna  2
Affiliations
Comment

Could asymptomatic carriers spread the SARS-CoV-2 infection? Experience from the Italian second wave

Luigi Atripaldi et al. J Transl Med. .
No abstract available

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Conflict of interest statement

PAA reports grants and personal fees from BMS, Roche-Genentech, Array; personal fees from MSD, Novartis, Merck Serono, Pierre Fabre, Incyte, Genmab, NewLink Genetics, Medimmune, AstraZeneca, Syndax, Sun Pharma, Sanofi, Idera, Ultimovacs, Sandoz, Immunocore, 4SC, Alkermes, Italfarmaco, Nektar and Boehringer-Ingelheim, all outside the submitted work. The other authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Box and Whiskers Plot of distribution of Ct data and viral load. In panel (a) distribution of Ct data compared to RdRP/S, N and E genes in 80 asymptomatic subjects (45 males, 35 females, median age 38.3, range 6–91) and 50 symptomatic subjects (24 males, 26 females, median age 46.7, range 6–96). In panel (b) distribution of Ct data compared to N1, N2, and N3 genetic regions and in panel (c) Box and Whiskers plot of viral load of 13 asymptomatic subjects (7 males, 6 females, median age 46.9, range 21–80) and 11 symptomatic subjects
See this image and copyright information in PMC

Comment on

References

    1. Cao S, Gan Y, Wang C, et al. Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China. Nat Commun. 2020;11(1):5917. doi: 10.1038/s41467-020-19802-w. - DOI - PMC - PubMed
    1. Gandhi M, Yokoe DS, Havlir DV. Asymptomatic transmission, the Achilles' heel of current strategies to control Covid-19. N Engl J Med. 2020;382(22):2158–2160. doi: 10.1056/NEJMe2009758. - DOI - PMC - PubMed
    1. Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature. 2020;581(7809):465–469. doi: 10.1038/s41586-020-2196-x. - DOI - PubMed
    1. Arons MM, Hatfield KM, Reddy SC, et al. Public Health-Seattle and King County and CDC COVID-19 investigation team. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. 2020;382(22):2081–2090. doi: 10.1056/NEJMoa2008457. - DOI - PMC - PubMed
    1. He D, Zhao S, Lin Q, et al. The relative transmissibility of asymptomatic COVID-19 infections among close contacts. Int J Infect Dis. 2020;94:145–147. doi: 10.1016/j.ijid.2020.04.034. - DOI - PMC - PubMed