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. 2021 Mar 3:1-9.
doi: 10.1017/S0033291721000957. Online ahead of print.

Understanding different trajectories of mental health across the general population during the COVID-19 pandemic

Affiliations

Understanding different trajectories of mental health across the general population during the COVID-19 pandemic

Rob Saunders et al. Psychol Med. .

Abstract

Background: The COVID-19 pandemic and nationally mandated restrictions to control the virus have been associated with increased mental health issues. However, the differential impact of the pandemic and lockdown on groups of individuals, and the personal characteristics associated with poorer outcomes are unknown.

Method: Data from 21 938 adults in England who participated in a stratified cohort study were analysed. Trajectories of depression and anxiety symptoms were identified using growth mixture modelling. Multinomial and logistic regression models were constructed to identify sociodemographic and personality-related risk factors associated with trajectory class membership.

Results: Four trajectories of depression and five for anxiety were identified. The most common group presented with low symptom severity throughout, other classes were identified that showed: severe levels of symptoms which increased; moderate symptoms throughout; worsening mental health during lockdown but improvements after lockdown ended; and for anxiety only, severe initial anxiety that decreased quickly during lockdown. Age, gender, ethnicity, income, previous diagnoses, living situation, personality factors and sociability were associated with different trajectories.

Conclusions: Nearly 30% of participants experienced trajectories with symptoms in the clinical range during lockdown, and did not follow the average curve or majority group, highlighting the importance of differential trajectories. Young, female, outgoing and sociable people and essential workers experienced severe anxiety around the announcement of lockdown which rapidly decreased. Younger individuals with lower incomes and previous mental health diagnoses experienced higher and increasing levels of symptoms. Recognising the likely symptom trajectories for such groups may allow for targeted care or interventions.

Keywords: COVID-19; Cohort study; lockdown; mental health outcomes; trajectories.

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Figures

Fig. 1.
Fig. 1.
GMM class solution trajectories (GAD-7 and PHQ-9).

References

    1. Allen, J., Balfour, R., Bell, R., & Marmot, M. (2014). Social determinants of mental health. International Review of Psychiatry, 26(4), 392–407. 10.3109/09540261.2014.928270 - DOI - PubMed
    1. Asparouhov, T., & Muthen, B. (2007). Testing for informative weights and weights trimming in multivariate modeling with survey data. Retrieved 01/02/2021 (http://www.statmodel.com/download/JSM2007000745.pdf).
    1. Barnett, K., Mercer, S. W., Norbury, M., Watt, G., Wyke, S., & Guthrie, B. (2012). Epidemiology of multimorbidity and implications for health care, research, and medical education: A cross-sectional study. The Lancet, 380(9836), 37–43. 10.1016/S0140-6736(12)60240-2 - DOI - PubMed
    1. Brooks, S. K., Webster, R. K., Smith, L. E., Woodland, L., Wessely, S., Greenberg, N., & Rubin, G. J. (2020). The psychological impact of quarantine and how to reduce it: Rapid review of the evidence. The Lancet, 395(10227), 912–920. 10.1016/S0140-6736(20)30460-8 - DOI - PMC - PubMed
    1. Bu, F., Steptoe, A., & Fancourt, D. (2020). Loneliness during lockdown: trajectories and predictors during the COVID-19 pandemic in 35712 adults in the UK, 1–19. 10.1101/2020.05.29.20116657 - DOI - PMC - PubMed