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Multicenter Study
. 2021 Jun;30(11-12):1742-1750.
doi: 10.1111/jocn.15733. Epub 2021 Mar 17.

Health-related quality of life of COVID-19 patients after discharge: A multicenter follow-up study

Guangbo Qu  1 , Qi Zhen  2 , Wenjun Wang  2 , Song Fan  3 , Qibing Wu  4 , Chengyuan Zhang  5 , Bao Li  6 , Gang Liu  7 , Yafen Yu  2 , Yonghuai Li  8 , Liang Yong  2 , Baojing Lu  9 , Zhen Ding  10 , Huiyao Ge  2 , Yiwen Mao  2 , Weiwei Chen  2 , Qiongqiong Xu  2 , Ruixue Zhang  2 , Lu Cao  2 , Shirui Chen  2 , Haiwen Li  11 , Hui Zhang  2 , Xia Hu  2 , Jing Zhang  12 , Yonglian Wang  12 , Hong Zhang  13 , Chaozhao Liang  3 , Liangdan Sun  14 , Yehuan Sun  1
Affiliations
Multicenter Study

Health-related quality of life of COVID-19 patients after discharge: A multicenter follow-up study

Guangbo Qu et al. J Clin Nurs. 2021 Jun.

Abstract

Aims and objectives: To determine the health-related quality of life (HRQoL) of COVID-19 patients after discharge and its predicting factors.

Background: COVID-19 has caused a worldwide pandemic and led a huge impact on the health of human and daily life. It has been demonstrated that physical and psychological conditions of hospitalised COVID-19 patients are impaired, but the studies focus on physical and psychological conditions of COVID-19 patients after discharge from hospital are rare.

Design: A multicentre follow-up study.

Methods: This was a multicentre follow-up study of COVID-19 patients who had discharged from six designated hospitals. Physical symptoms and HRQoL were surveyed at first follow-up (the third month after discharge). The latest multiple laboratory findings were collected through medical examination records. This study was performed and reported in accordance with STROBE checklist.

Results: Three hundred eleven patients (57.6%) were reported with one or more physical symptoms. The scores of HRQoL of COVID-19 patients at third month after discharge, except for the dimension of general health, were significantly lower than Chinese population norm (p < .001). Results of logistic regression showed that female (odds ratio (OR): 1.79, 95% confidence interval (CI): 1.04-3.06), older age (≥60 years) (OR: 2.44, 95% CI: 1.33-4.47) and the physical symptom after discharge (OR: 40.15, 95% CI: 9.68-166.49) were risk factors for poor physical component summary; the physical symptom after discharge (OR: 6.68, 95% CI: 4.21-10.59) was a risk factor for poor mental component summary.

Conclusions: Health-related quality of life of discharged COVID-19 patients did not come back to normal at third month after discharge and affected by age, sex and the physical symptom after discharge.

Relevance to clinical practice: Healthcare workers should pay more attention to the physical and psychological rehabilitation of discharged COVID-19 patients. Long-term follow-up on COVID-19 patients after discharge is needed to determine the long-term impact of COVID-19.

Keywords: COVID-19; SARS-CoV-2; clinical; discharge; health-related quality of life.

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Conflict of interest statement

All authors disclosed no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flow chart of this study
See this image and copyright information in PMC

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