Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Mar 5;27(2):126-130.
doi: 10.1097/PRA.0000000000000508.

Postviral Depression

Madison L Collins, Grace A Cheney, Jennifer L Yehl, Gregory A Sullivan, Jonathan T Stewart, Glenn Catalano
Review

Postviral Depression

Madison L Collins et al. J Psychiatr Pract. .

Abstract

A previously healthy 68-year-old man rapidly developed a severe melancholic depression following influenza infection. There is an evolving understanding of the complex and possibly bidirectional relationship between depression and inflammation. We review the literature concerning this relationship in the context of viral infection and discuss possible implications for treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158:725–730.
    1. Safren SA, Gershuny BS, Hendriksen E. Symptoms of posttraumatic stress and death anxiety in persons with HIV and medication adherence difficulties. AIDS Patient Care STDS. 2003;17:657–664.
    1. Younossi Z, Park H, Henry L, et al. Extrahepatic manifestations of hepatitis C: a meta-analysis of prevalence, quality of life, and economic burden. Gastroenterology. 2016;150:1599–1608.
    1. Coughlin SS. Anxiety and depression: linkages with viral diseases. Public Health Rev. 2012;34:7.
    1. Gale SD, Berrett AN, Erickson LD, et al. Association between virus exposure and depression in US adults. Psychiatry Res. 2018;261:73–79.

LinkOut - more resources