Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr 7;16(4):639-641.
doi: 10.2215/CJN.12110720. Epub 2021 Mar 3.

Incorporating Patient Preferences via Bayesian Decision Analysis

Affiliations

Incorporating Patient Preferences via Bayesian Decision Analysis

Shomesh E Chaudhuri et al. Clin J Am Soc Nephrol. .
No abstract available

Keywords: Bayesian decision analysis; clinical trial; patient preferences; quality of life; randomized controlled trials.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Optimal size and power for two-armed balanced fixed sample clinical trial according to Bayesian decision analysis (BDA) in which the expected loss of false positives and negatives is jointly minimized. The left figure displays the expected cost to patients as a function of the false positive rate (the BDA optimal value minimizes this expected cost), and the right figure displays the true positive rate (or power) as a function of the false positive rate. For an interactive version of these graphs, see the Supplemental Material.

Similar articles

Cited by

References

    1. Isakov L, Lo AW, Montazerhodjat V: Is the FDA too conservative or too aggressive?: A Bayesian decision analysis of clinical trial design. J Econom 211: 117–136, 2019
    1. Montazerhodjat V, Chaudhuri SE, Sargent DJ, Lo AW: Use of Bayesian decision analysis to minimize harm in patient-centered randomized clinical trials in oncology. JAMA Oncol 3: e170123, 2017 - PMC - PubMed
    1. Chaudhuri SE, Ho MP, Irony T, Sheldon M, Lo AW: Patient-centered clinical trials. Drug Discov Today 2: 395–401, 2018 - PubMed
    1. Chaudhuri SE, Lo AW, Xiao D, Xu Q: Bayesian adaptive clinical trials for anti‐infective therapeutics during epidemic outbreak [published online ahead of print May 14, 2020]. Harvard Data Sci Rev 10.1162/99608f92.7656c213 - DOI
    1. Chaudhuri SE, Lo AW: Bayesian adaptive patient-centered clinical trials. 2019